EEPD1 and GRIP1

Data Source:
BioGRID (two hybrid)

		EEPD1	GRIP1
Description		endonuclease/exonuclease/phosphatase family domain containing 1	glutamate receptor interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Anchored Component Of Plasma Membrane	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Dendrite Cytoplasmic Vesicle Neuron Projection Perikaryon Membrane Raft Postsynaptic Membrane Glutamatergic Synapse
	Molecular Function	DNA Binding Protein Binding	Protein Binding Beta-catenin Binding Protein C-terminus Binding Signaling Receptor Complex Adaptor Activity Glucocorticoid Receptor Binding
	Biological Process	DNA Repair Positive Regulation Of Cholesterol Efflux	Dendrite Development Intracellular Signal Transduction Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Positive Regulation Of Neuron Projection Arborization
Pathways		NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	Trafficking of GluR2-containing AMPA receptors
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Fibrinogen levels ( 28107422 26561523) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) LDL cholesterol levels ( 32203549) Mean spheric corpuscular volume ( 32888494) Obesity-related traits ( 23251661) Platelet count ( 21507922) Pulse pressure ( 30224653) Refractive error ( 32231278) Reticulocyte count ( 32888494) Schizophrenia ( 30285260)	Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		2 interacting genes: APP GRIP1	42 interacting genes: AGAP2 AR CARM1 CSPG4 DEPDC1B DZIP3 EEPD1 EFNA5 EFNB1 EFNB2 EP300 ESR1 FGF12 FLII GPR37 GRIA1 GRIA3 GRIA4 GRIK1 GRIK2 GRIPAP1 GRM2 GRM3 GRM7 H3C1 HUS1 IRF3 MFAP3 NCOA6 NEK6 NR3C1 NUMBL PICK1 PPARG PRKD2 PRMT1 RXRA THRA UBE2I VDR WDR6 XDH
Entrez ID		80820	23426
HPRD ID		13884	19086
Ensembl ID		ENSG00000122547	ENSG00000155974
Uniprot IDs		Q7L9B9	Q9Y3R0
PDB IDs			2JIL
Enriched GO Terms of Interacting Partners?
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