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CXXC4 and DVL1
Data Source:
HPRD
(in vitro, in vivo, two hybrid)
CXXC4
DVL1
Description
CXXC finger protein 4
dishevelled segment polarity protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytoplasmic Vesicle
Cytosol
Microtubule
Postsynaptic Density
Lateral Plasma Membrane
Clathrin-coated Vesicle
Growth Cone
Cytoplasmic Vesicle
Neuron Projection
Neuronal Cell Body
Dendritic Spine
Synapse
Schaffer Collateral - CA1 Synapse
Presynapse
Glutamatergic Synapse
Wnt Signalosome
Molecular Function
Zinc Ion Binding
Methyl-CpG Binding
PDZ Domain Binding
Molecular_function
Frizzled Binding
Protein Binding
Beta-catenin Binding
Enzyme Binding
Protein Kinase Binding
Identical Protein Binding
Biological Process
Zygotic Specification Of Dorsal/ventral Axis
Wnt Signaling Pathway
Negative Regulation Of Wnt Signaling Pathway
Regulation Of Neurotransmitter Levels
Positive Regulation Of Protein Phosphorylation
Regulation Of Transcription, DNA-templated
Negative Regulation Of Protein Kinase Activity
Neurotransmitter Secretion
Axon Guidance
Heart Development
Neuromuscular Junction Development
Positive Regulation Of Neuron Projection Development
Neural Tube Development
Convergent Extension Involved In Neural Plate Elongation
Cytoplasmic Microtubule Organization
Negative Regulation Of Protein Binding
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Localization To Nucleus
Social Behavior
Protein Localization To Microtubule
Intracellular Signal Transduction
Non-canonical Wnt Signaling Pathway
Receptor Clustering
Positive Regulation Of Transcription By RNA Polymerase II
Collateral Sprouting
Axon Extension
Dendrite Morphogenesis
Synapse Organization
Protein Stabilization
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Prepulse Inhibition
Dendritic Spine Morphogenesis
Skeletal Muscle Acetylcholine-gated Channel Clustering
Negative Regulation Of Canonical Wnt Signaling Pathway
Cochlea Morphogenesis
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Presynapse Assembly
Positive Regulation Of Neuron Projection Arborization
Regulation Of Cellular Protein Localization
Beta-catenin Destruction Complex Disassembly
Positive Regulation Of Protein Localization To Presynapse
Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Excitatory Postsynaptic Potential
Pathways
TCF dependent signaling in response to WNT
WNT mediated activation of DVL
PCP/CE pathway
PCP/CE pathway
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
RHO GTPases Activate Formins
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS
Chronotype (
30696823
)
Menarche (age at onset) (
27182965
)
Metabolite levels (
23823483
)
Molybdenum levels (
26025379
)
Rosacea symptom severity (
29771307
)
Schizophrenia (
30285260
)
Inflammatory bowel disease (
28067908
)
Nicotine dependence (
32281736
)
Ulcerative colitis (
28067908
)
Interacting Genes
3 interacting genes:
APP
DVL1
FBXO25
43 interacting genes:
ANXA7
ARRB1
ATN1
AXIN1
BAG3
BRD7
BUB1
CCDC88C
CSNK1D
CSNK1E
CSNK2A1
CTNNB1
CXXC4
DAAM1
DAB2
DVL3
DYNLT1
EPS8
FBXW7
FRAT1
HDHD2
HECW1
KLHL12
LRRK2
MLH3
MSH2
NCK2
NEDD4
PPM1A
PSMA3
RAC1
RB1
SIPA1
SMAD1
SMAD2
SMAD3
SMAD4
SMAD7
SMYD1
TRIM69
USP13
VANGL1
VANGL2
Entrez ID
80319
1855
HPRD ID
16773
03220
Ensembl ID
ENSG00000168772
ENSG00000107404
Uniprot IDs
J9JIF5
O14640
PDB IDs
6TTK
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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