EFHD1 and RAB27B

Data Source:
BioGRID (affinity chromatography technology)

		EFHD1	RAB27B
Description		EF-hand domain family member D1	RAB27B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane	Late Endosome Golgi Stack Plasma Membrane Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Platelet Dense Granule Membrane Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane Axon Cytoplasm
	Molecular Function	Calcium Ion Binding Calcium Ion Sensor Activity	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Neuron Projection Development Regulation Of Cellular Hyperosmotic Salinity Response	Platelet Degranulation Melanosome Transport Positive Regulation Of Exocytosis Synaptic Vesicle Endocytosis Multivesicular Body Sorting Pathway Anterograde Axonal Protein Transport
Pathways			Platelet degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Alanine transaminase levels ( 29403010) Aspartate aminotransferase levels ( 29403010) Coronary artery disease ( 32469254) Gamma glutamyl transferase levels ( 29403010) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656 30285260)	Adult body size ( 32376654) Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 28892062) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Depression ( 29700475) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		1 interacting genes: PSEN1	11 interacting genes: DHPS GORASP2 MLPH MYRIP RPH3A RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D
Entrez ID		80303	5874
HPRD ID		13265	04846
Ensembl ID		ENSG00000115468	ENSG00000041353
Uniprot IDs		Q8WYH2 Q9BUP0	O00194
PDB IDs			2F7S
Enriched GO Terms of Interacting Partners?
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