RAB27B and SYTL5

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid)

		RAB27B	SYTL5
Description		RAB27B, member RAS oncogene family	synaptotagmin like 5
Image			No pdb structure
GO Annotations	Cellular Component	Late Endosome Golgi Stack Plasma Membrane Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Platelet Dense Granule Membrane Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane Axon Cytoplasm	Plasma Membrane Exocytic Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding	Protein Binding Phospholipid Binding Neurexin Family Protein Binding Metal Ion Binding
	Biological Process	Platelet Degranulation Melanosome Transport Positive Regulation Of Exocytosis Synaptic Vesicle Endocytosis Multivesicular Body Sorting Pathway Anterograde Axonal Protein Transport	Intracellular Protein Transport Exocytosis
Pathways		Platelet degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Adult body size ( 32376654) Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 28892062) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Depression ( 29700475) Serum uric acid levels in response to allopurinol in gout ( 25676789)	Anorexia nervosa ( 23568457) Erectile dysfunction and prostate cancer treatment ( 20932654)
Interacting Genes		11 interacting genes: DHPS GORASP2 MLPH MYRIP RPH3A RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D	9 interacting genes: CCDC85A CEP70 RAB27A RAB27B RAB3A RAB6A TRIM54 WAC YIF1A
Entrez ID		5874	94122
HPRD ID		04846	06736
Ensembl ID		ENSG00000041353	ENSG00000147041
Uniprot IDs		O00194	Q8TDW5
PDB IDs		2F7S
Enriched GO Terms of Interacting Partners?
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