ANKRD55 and ANKS1A

  • Data Source:
  • BioGRID (two hybrid)

ANKRD55

ANKS1A

Description ankyrin repeat domain 55 ankyrin repeat and sterile alpha motif domain containing 1A
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (cognitive decline) ( 23535033)
  • Celiac disease or Rheumatoid arthritis ( 21383967)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • IgA levels ( 28628107)
  • IgG glycosylation ( 23382691)
  • Immature fraction of reticulocytes ( 32888494)
  • Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761)
  • Lung function (FEV1) ( 30061609)
  • Macular thickness ( 30535121)
  • Monocyte count ( 27863252)
  • Monocyte percentage of white cells ( 32888494)
  • Multiple sclerosis ( 31604244 24076602 27386562)
  • Optic disc size ( 31809533)
  • Pediatric autoimmune diseases ( 26301688)
  • Post-traumatic stress disorder ( 27167565)
  • Reticulocyte fraction of red cells ( 32888494)
  • Rheumatoid arthritis ( 30423114 30572963 23143596 24390342 20453842)
  • Rheumatoid arthritis (ACPA-negative) ( 23143596)
  • Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)
  • Sero-negative rheumatoid arthritis ( 28706201)
  • Triglycerides ( 20686565)
  • Type 2 diabetes ( 27189021 22885922 26961502 29358691 30297969 26818947 32499647 30718926 28869590)
  • Urate levels ( 23263486)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
  • Brain morphology (MOSTest) ( 32665545)
  • Coronary artery disease ( 24262325)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 21378990)
  • Height ( 28552196 23563607 18391951)
  • Mean platelet volume ( 32888494)
  • Non-small cell lung cancer ( 23144319)
  • Obesity-related traits ( 23251661)
  • Platelet distribution width ( 32888494)
  • Refractive error ( 32231278)
  • Subcortical volume (MOSTest) ( 32665545)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412)
Interacting Genes 22 interacting genes: ABI2 ANKS1A BACH2 BANP BOLA2 BOLA2B CABP5 CFAP206 CLIC3 FHL2 FHL5 FRS3 HGS HSF2BP NCK2 NOXA1 PFDN5 PTK6 TEKT4 TRIM23 ZMYND19 ZSCAN1 99 interacting genes: ABI2 ADGRL1 ALDOC ANKRD55 ARAP3 ARHGAP10 BCAR1 BLZF1 C17orf50 C19orf54 C22orf39 C3orf36 C9orf152 CADPS CCDC184 CCDC33 CHCHD3 CYSRT1 DAB2IP DOK3 EGFR ERBB2 ERBB4 ESM1 FAM217B FAM221A FAM86C1P FCHSD2 FHL5 GOLGA2 GPRIN2 HOXA1 HOXC8 ID3 IKZF3 ISCA2 ITIH6 KCTD9 KEAP1 KIAA1328 KLF15 KLHL26 KPRP KRT31 KRT34 KRT39 KRT75 KRT83 KRTAP10-11 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP19-7 KRTAP4-2 KRTAP6-2 KRTAP9-3 LASP1 LHX2 LNX1 MBD3L1 MED20 MEOX2 MID2 MTUS2 NADSYN1 NBPF19 NEDD9 NHLRC2 NOTCH2NLA NUTM2F PIK3R3 PRDM6 PRKAR1B RANBP3 RB1 RIN1 RNF144B RORB RUSC1 SCN5A SH3KBP1 SHISA6 SLC15A2 SMARCD1 SORBS3 SPATA12 SPRED1 TOX2 TP53BP1 TRIM29 TRIT1 UBC USP54 USP7 YWHAG ZBTB32 ZBTB42 ZC2HC1C ZNF135
Entrez ID 79722 23294
HPRD ID 07758 10610
Ensembl ID ENSG00000164512 ENSG00000064999
Uniprot IDs Q3KP44 Q05CP0 Q92625
PDB IDs 2LMR 2MYQ 6F7O
Enriched GO Terms of Interacting Partners?
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