CERS4 and TOMM6

Data Source:
BioGRID (two hybrid)

		CERS4	TOMM6
Description		ceramide synthase 4	translocase of outer mitochondrial membrane 6
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex
	Molecular Function	DNA Binding Protein Binding N-acyltransferase Activity Sphingosine N-acyltransferase Activity	Protein Binding
	Biological Process	Sphingolipid Biosynthetic Process Ceramide Biosynthetic Process	Protein Transport Macroautophagy
Pathways		Sphingolipid de novo biosynthesis	Mitochondrial protein import PINK1-PRKN Mediated Mitophagy
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Metabolite levels ( 31628463) Red cell distribution width ( 32888494) Refractive error ( 32231278) Serum metabolite ratios in chronic kidney disease ( 29545352) Sphingolipid levels ( 26068415) Sphingomyelin levels ( 31551469) Thyroid stimulating hormone levels ( 30367059 32769997) Very long-chain saturated fatty acid levels (fatty acid 24:0) ( 25378659)
Interacting Genes		47 interacting genes: C1QL4 CCL4L2 CLEC1A COL4A5 CTXN3 CXCL16 CYB5R3 EMD FATE1 FCER1G FXYD6 FXYD6-FXYD2 GPR151 IER3IP1 IGFBP5 ITGAM JAGN1 LHFPL5 MS4A1 NAT8 NEU1 PLP2 PNLIPRP1 PTPN9 SCAMP5 SCD SERF1A SERF1B SERP2 SLC13A4 SLC29A2 SLC35A1 SLC35F6 SLC7A1 SMIM11A SMIM11B STX7 STX8 TEX264 TMEM119 TMEM176A TMEM254 TMEM72 TOMM6 TSPO2 UPK1B VAMP2	13 interacting genes: AQP6 C1orf159 CD68 CERS4 ERGIC3 FFAR3 GLP1R ODF4 SEC61A2 SLC10A1 SLC16A2 SLC18A2 TMEM14B
Entrez ID		79603	100188893
HPRD ID		13962	19464
Ensembl ID		ENSG00000090661	ENSG00000214736
Uniprot IDs		Q53HF9 Q9HA82	Q96B49
PDB IDs			7CK6
Enriched GO Terms of Interacting Partners?
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