GPANK1 and TTC19

Data Source:
BioGRID (two hybrid)

		GPANK1	TTC19
Description		G-patch domain and ankyrin repeats 1	tetratricopeptide repeat domain 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respirasome
	Molecular Function	Nucleic Acid Binding Protein Binding	Protein Binding
	Biological Process		Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly
Pathways
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Febrile seizures (MMR vaccine-related) ( 25344690) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)
Interacting Genes		89 interacting genes: ABI2 AKAP8L ANAPC11 AP1B1 AP2B1 APP BAG4 BHLHB9 C1QTNF2 CADPS CCDC184 CCDC33 CCDC85B CEACAM6 CYSRT1 DDI1 DHX15 DISC1 ECM1 EFS FAM166B FTO GOLGA2 GOLGA6L9 GRB2 HNRNPH1 HOMEZ HSF2BP HYI INKA1 INSC KANK2 KATNBL1 KCTD9 KRT75 KRTAP10-8 KRTAP12-2 KRTAP13-3 KRTAP19-5 KRTAP19-6 LDOC1 LIG4 LZTS2 MAGED1 MAGOHB MDFI MEOX1 MEOX2 METTL27 METTL6 MID2 MORN3 NADSYN1 NFKBID NR1H3 NUTM1 OIP5 PATZ1 PAX6 PBX4 PFDN5 PLAAT1 PNMA1 PPARA PPP4C PRDM6 PTH1R RIMBP3C RTL8C SORBS3 SPATA2 STMN3 STX5 TEPSIN TFCP2 TLE5 TRAF2 TRAPPC2L TRIM23 TRIM27 TSC1 TTC19 TTC23 VBP1 ZBTB16 ZBTB8OS ZMAT5 ZNF688 ZRANB1	44 interacting genes: AGXT APRT ATXN1 C20orf85 CCDC33 CHMP4A COA6 CYSLTR2 DMRT3 EIF4ENIF1 FAM136A FAM217B FH FTO GORASP2 GPANK1 HOXD12 HPS6 IHO1 L3MBTL3 LDB2 MLN MXRA8 NAB2 NME4 POU6F2 PRR35 RBP1 REL RUSC1 RXFP3 SH2D4A SHISA6 SLC22A18AS SMG9 SPRED1 TBX2 TCAP UBA1 UPF3B USP20 USP54 WASHC1 ZNF688
Entrez ID		7918	54902
HPRD ID		00810	07899
Ensembl ID		ENSG00000204438	ENSG00000011295
Uniprot IDs		A0A024RCU2 B2RA66 O95872	A0A024RD83 Q6DKK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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