TTC19 and EIF4ENIF1

Data Source:
BioGRID (two hybrid)

		TTC19	EIF4ENIF1
Description		tetratricopeptide repeat domain 19	eukaryotic translation initiation factor 4E nuclear import factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respirasome	P-body Nucleus Cytoplasm Cytosol Membrane PML Body Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Nuclear Export Signal Receptor Activity Protein Binding Kinase Binding
	Biological Process	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly	Protein Import Into Nucleus Negative Regulation Of Translation Stem Cell Population Maintenance Gene Silencing By RNA P-body Assembly Negative Regulation Of Neuron Differentiation MRNA Stabilization Nuclear Export Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of MiRNA Mediated Inhibition Of Translation
Pathways
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS			Age-related hearing impairment ( 24939585) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663)
Interacting Genes		44 interacting genes: AGXT APRT ATXN1 C20orf85 CCDC33 CHMP4A COA6 CYSLTR2 DMRT3 EIF4ENIF1 FAM136A FAM217B FH FTO GORASP2 GPANK1 HOXD12 HPS6 IHO1 L3MBTL3 LDB2 MLN MXRA8 NAB2 NME4 POU6F2 PRR35 RBP1 REL RUSC1 RXFP3 SH2D4A SHISA6 SLC22A18AS SMG9 SPRED1 TBX2 TCAP UBA1 UPF3B USP20 USP54 WASHC1 ZNF688	27 interacting genes: ATXN1 CDK6 CFAP206 DEF6 DTX2 EFHC1 EIF3E EIF4E EIF4E2 FANCL FDPS HNRNPF KRT19 L3MBTL2 MGAT5B OIP5 PRR20A PRR20B PRR20C PRR20D PRR20E SMAD3 SPAG5 TCHP TTC19 TXLNA USP2
Entrez ID		54902	56478
HPRD ID		07899	10456
Ensembl ID		ENSG00000011295	ENSG00000184708
Uniprot IDs		A0A024RD83 Q6DKK2	A0A024R1K0 Q9NRA8
PDB IDs			5ANR 6F9W 6X2R
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?