ZNF232 and NR2E3

Data Source:
BioGRID (two hybrid)

		ZNF232	NR2E3
Description		zinc finger protein 232	nuclear receptor subfamily 2 group E member 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Visual Perception Phototransduction Negative Regulation Of Cell Population Proliferation Cell Differentiation Intracellular Receptor Signaling Pathway Eye Photoreceptor Cell Development Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development Retina Development In Camera-type Eye
Pathways
Drugs
Diseases			Vitreoretinal degeneration, including: Stickler syndrome type I (STL1); Stickler syndrome type II (STL2); Snowflake vitreoretinal degeneration (SVD); Wagner syndrome 1 (WGN1); Knobloch syndrome (KNO); Enhanced S-cone syndrome (ESCS); Autosomal dominant vitreoretinochoroidopathy (ADVIRC) Retinitis pigmentosa (RP)
GWAS		PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Macular thickness ( 30535121) Metabolite levels (HVA/MHPG ratio) ( 23319000) Red blood cell count ( 32888494)
Interacting Genes		10 interacting genes: EMD FXR2 MTUS2 NR2E3 PPCDC TRAK1 YY1 ZNF24 ZNF446 ZSCAN32	29 interacting genes: BCL11A CDK9 CRX DEDD2 DHX30 ELAVL2 HDAC1 HDAC3 HOXC13 IRF9 MYBBP1A NCOR1 NR1D1 NR3C1 NRL POLR3D PPARG RARA RBBP4 RBBP7 RBFOX2 RBL1 RXRA RXRB SIN3A SNAPC1 TBL3 WDR5 ZNF232
Entrez ID		7775	10002
HPRD ID		15755	05132
Ensembl ID		ENSG00000167840	ENSG00000278570
Uniprot IDs		I3L4J6 Q9UNY5	F1D8Q9 Q9Y5X4
PDB IDs			4LOG
Enriched GO Terms of Interacting Partners?
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