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NR2E3 and SNAPC1
Data Source:
BioGRID
(two hybrid)
NR2E3
SNAPC1
Description
nuclear receptor subfamily 2 group E member 3
small nuclear RNA activating complex polypeptide 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Regulator Complex
Nucleoplasm
Nucleolus
SnRNA-activating Protein Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Steroid Hormone Receptor Activity
Nuclear Receptor Activity
Protein Binding
Zinc Ion Binding
Sequence-specific DNA Binding
RNA Polymerase III General Transcription Initiation Factor Activity
Protein Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Sequence-specific DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Signal Transduction
Visual Perception
Phototransduction
Negative Regulation Of Cell Population Proliferation
Cell Differentiation
Intracellular Receptor Signaling Pathway
Eye Photoreceptor Cell Development
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Transcription By RNA Polymerase II
Anatomical Structure Development
Retina Development In Camera-type Eye
SnRNA Transcription By RNA Polymerase II
SnRNA Transcription By RNA Polymerase III
Pathways
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
Vitreoretinal degeneration, including: Stickler syndrome type I (STL1); Stickler syndrome type II (STL2); Snowflake vitreoretinal degeneration (SVD); Wagner syndrome 1 (WGN1); Knobloch syndrome (KNO); Enhanced S-cone syndrome (ESCS); Autosomal dominant vitreoretinochoroidopathy (ADVIRC)
Retinitis pigmentosa (RP)
GWAS
Hematocrit (
32888494
)
Hemoglobin (
32888494
)
Macular thickness (
30535121
)
Metabolite levels (HVA/MHPG ratio) (
23319000
)
Red blood cell count (
32888494
)
Chronotype (
30696823
)
Metabolite levels (
23823483
)
Interacting Genes
29 interacting genes:
BCL11A
CDK9
CRX
DEDD2
DHX30
ELAVL2
HDAC1
HDAC3
HOXC13
IRF9
MYBBP1A
NCOR1
NR1D1
NR3C1
NRL
POLR3D
PPARG
RARA
RBBP4
RBBP7
RBFOX2
RBL1
RXRA
RXRB
SIN3A
SNAPC1
TBL3
WDR5
ZNF232
14 interacting genes:
CCDC6
EXOC8
HAT1
HOXA10
HSF2BP
NR2E3
RB1
RHOXF2
SAAL1
SNAPC3
SNAPC4
SNAPC5
TBP
TRIM29
Entrez ID
10002
6617
HPRD ID
05132
08998
Ensembl ID
ENSG00000278570
ENSG00000023608
Uniprot IDs
F1D8Q9
Q9Y5X4
B2RC42
Q16533
PDB IDs
4LOG
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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