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XPO1 and SNUPN
Data Source:
HPRD
(in vitro, in vivo)
XPO1
SNUPN
Description
exportin 1
snurportin 1
Image
GO Annotations
Cellular Component
Kinetochore
Nucleus
Nuclear Envelope
Annulate Lamellae
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Cajal Body
Membrane
Nuclear Membrane
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Host Cell
Ribonucleoprotein Complex
Nuclear Pore
Cytosol
Molecular Function
RNA Binding
Nuclear Export Signal Receptor Activity
Protein Binding
RNA Cap Binding
Protein Binding
Nuclear Import Signal Receptor Activity
Biological Process
Ribosomal Subunit Export From Nucleus
Ribosomal Large Subunit Export From Nucleus
Ribosomal Small Subunit Export From Nucleus
Protein Export From Nucleus
Nucleocytoplasmic Transport
Viral Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Ribosome Biogenesis
Regulation Of MRNA Stability
MRNA Transport
Intracellular Transport Of Virus
Spliceosomal SnRNP Assembly
Protein Import Into Nucleus
Import Into Nucleus
SnRNA Import Into Nucleus
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Rev-mediated nuclear export of HIV RNA
NEP/NS2 Interacts with the Cellular Export Machinery
Downregulation of TGF-beta receptor signaling
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Deactivation of the beta-catenin transactivating complex
HuR (ELAVL1) binds and stabilizes mRNA
RHO GTPases Activate Formins
MAPK6/MAPK4 signaling
Mitotic Prometaphase
Cyclin A/B1/B2 associated events during G2/M transition
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
EML4 and NUDC in mitotic spindle formation
snRNP Assembly
Drugs
Selinexor
Diseases
GWAS
Atrial fibrillation (
29892015
)
Eosinophil counts (
32888494
27863252
)
Erectile dysfunction (
30583798
)
Mean reticulocyte volume (
32888494
)
Neutrophil count (
32888494
)
Sum eosinophil basophil counts (
27863252
)
Systemic lupus erythematosus (
28714469
)
Urinary sodium excretion (
31409800
)
White blood cell count (
32888494
)
Interacting Genes
80 interacting genes:
ABL1
ADAR
AGFG1
AHR
ANP32A
ANP32B
APC
ATF2
BECN1
BIRC5
BRCA2
CCND1
CDC25A
CDC42
CDCA4
CDKN1B
CHEK1
CHORDC1
CIITA
CRK
DDX3X
DESI1
DR1
E2F4
E2F5
EIF5A
ERF
FBXO7
FOXO4
HDAC3
HNF4A
HSPA9
HSPB1
IRF5
KIF17
LINC01554
MAPK6
NF2
NMD3
NPM1
NUCB1
NUCB2
NUP153
NUP214
NUP50
NUP62
NXF3
NXT1
ORC1
PHAX
PHB
PKIA
RAD51
RAN
RANBP2
RANBP3
RCC1
RCN2
RGS14
RIC8A
RPS6KB1
SERPINB1
SERTAD2
SIRT2
SMAD1
SMARCB1
SMURF1
SMURF2
SNUPN
SOX2
STAT1
STRADA
SUMO1
SUMO2
TERF2IP
TERT
TOP2A
TOP2B
TP53
TP73
16 interacting genes:
DBN1
DDX20
ENO2
GCNT3
KPNB1
MEX3B
PAFAH1B2
PEX5
RAN
RNF126
RPL17
SMN1
SNRPB
TNNT3
XPO1
ZPR1
Entrez ID
7514
10073
HPRD ID
03975
07441
Ensembl ID
ENSG00000082898
ENSG00000169371
Uniprot IDs
B3KWD0
O14980
O95149
PDB IDs
1W9C
2L1L
3GB8
4BSM
4BSN
5DIS
6TVO
1XK5
2P8Q
2Q5D
2QNA
3GB8
3GJX
3LWW
3NBY
3NBZ
3NC0
5DIS
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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