CIDEA and UCP1

Data Source:
HPRD (in vitro)

		CIDEA	UCP1
Description		cell death inducing DFFA like effector a	uncoupling protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Envelope Lipid Droplet Cytosol	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	Protein Homodimerization Activity	Oxidative Phosphorylation Uncoupler Activity Transmembrane Transporter Activity Purine Ribonucleotide Binding Long-chain Fatty Acid Binding Cardiolipin Binding
	Biological Process	Temperature Homeostasis Negative Regulation Of Cytokine Production Lipid Metabolic Process Apoptotic Process Cell Death Positive Regulation Of Sequestering Of Triglyceride Lipid Storage Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Production Lipid Droplet Organization Response To Stilbenoid Regulation Of Apoptotic Process Negative Regulation Of Lipid Catabolic Process Cellular Response To Cold Negative Regulation Of Cold-induced Thermogenesis Negative Regulation Of Execution Phase Of Apoptosis Regulation Of Apoptotic DNA Fragmentation	Diet Induced Thermogenesis Regulation Of Transcription By RNA Polymerase II Response To Temperature Stimulus Response To Cold Response To Nutrient Levels Cellular Response To Hormone Stimulus Cellular Response To Reactive Oxygen Species Brown Fat Cell Differentiation Cellular Response To Cold Cellular Response To Fatty Acid Positive Regulation Of Cold-induced Thermogenesis Proton Transmembrane Transport Regulation Of Reactive Oxygen Species Biosynthetic Process Mitochondrial Transmembrane Transport Adaptive Thermogenesis
Pathways		Lipid particle organization	The fatty acid cycling model The proton buffering model
Drugs
Diseases
GWAS		Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297)	Malaria ( 31844061)
Interacting Genes		5 interacting genes: CIDEB CIDEC MIEF2 UCP1 ZBTB16	2 interacting genes: CIDEA TOMM20
Entrez ID		1149	7350
HPRD ID		08380	00221
Ensembl ID		ENSG00000176194	ENSG00000109424
Uniprot IDs		B3KVA2 O60543 Q8N5P9	P25874 Q4KMT7
PDB IDs		2EEL
Enriched GO Terms of Interacting Partners?
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