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UBE2V2 and MALT1
Data Source:
BioGRID
(pull down)
UBE2V2
MALT1
Description
ubiquitin conjugating enzyme E2 V2
MALT1 paracaspase
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
UBC13-MMS2 Complex
Extracellular Exosome
Fibrillar Center
Polkadots
Nucleus
Cytoplasm
Cytosol
CBM Complex
Protein-containing Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Protease Binding
Cysteine-type Endopeptidase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Peptidase Activity
Kinase Activator Activity
Identical Protein Binding
Protein Self-association
Biological Process
Protein Polyubiquitination
DNA Double-strand Break Processing
Regulation Of DNA Repair
Postreplication Repair
Double-strand Break Repair Via Nonhomologous End Joining
Positive Regulation Of Neuron Projection Development
Protein Ubiquitination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Error-free Postreplication DNA Repair
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of DNA Repair
Positive Regulation Of Synapse Assembly
Protein K63-linked Ubiquitination
B-1 B Cell Differentiation
Stimulatory C-type Lectin Receptor Signaling Pathway
Positive Regulation Of T Cell Cytokine Production
Proteolysis
Defense Response
Activation Of NF-kappaB-inducing Kinase Activity
Response To Fungus
Protein Ubiquitination
Positive Regulation Of Protein Ubiquitination
Lipopolysaccharide-mediated Signaling Pathway
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-2 Production
Fc-epsilon Receptor Signaling Pathway
T Cell Proliferation
B Cell Activation
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Innate Immune Response
T Cell Receptor Signaling Pathway
Regulation Of T Cell Receptor Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Nuclear Export
Positive Regulation Of T-helper 17 Cell Differentiation
Pathways
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
Formation of Incision Complex in GG-NER
G2/M DNA damage checkpoint
E3 ubiquitin ligases ubiquitinate target proteins
Antigen processing: Ubiquitination & Proteasome degradation
Activation of NF-kappaB in B cells
Activation of NF-kappaB in B cells
Downstream TCR signaling
FCERI mediated NF-kB activation
FCERI mediated NF-kB activation
CLEC7A (Dectin-1) signaling
CLEC7A/inflammasome pathway
Drugs
Diseases
GWAS
Height (
31562340
)
Metabolite levels (
23823483
)
Multiple sclerosis (
31604244
21833088
)
Interacting Genes
33 interacting genes:
BCL10
DZIP3
EGFR
HLTF
IGSF21
LNX1
LRIF1
MALT1
MKRN3
MOB4
MUL1
OTUB1
RC3H1
RC3H2
RFFL
RNF144A
RNF2
RNF8
SHPRH
SIAH1
SIAH2
STUB1
SUV39H2
TP53
TRAF2
TRIM21
TRIM5
TRIM54
TRIM63
UBC
UBE2N
XIAP
ZNRF1
16 interacting genes:
BCL10
CARM1
FEM1A
FEM1C
KDM1A
PRMT6
RBCK1
RELB
SQSTM1
SUV39H1
TRAF2
TRAF6
UBC
UBE2N
UBE2V2
USP2
Entrez ID
7336
10892
HPRD ID
04300
06892
Ensembl ID
ENSG00000169139
ENSG00000172175
Uniprot IDs
A0M8W4
Q15819
A8K5S1
Q9UDY8
PDB IDs
1J74
1J7D
1ZGU
3VON
4NR3
4NRG
4NRI
4ONL
4ONM
4ONN
4ORH
5AIT
2G7R
3BFO
3K0W
3UO8
3UOA
3V4O
3V55
4I1P
4I1R
6F7I
6GK2
6H4A
6YN8
6YN9
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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