Description |
ubiquitin conjugating enzyme E2 L3 |
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Apolipoprotein A1 levels ( 32203549)
- Atrial fibrillation ( 30061737)
- Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
- Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644)
- Glucagon levels in response to oral glucose tolerance test (120 minutes) ( 29093273)
- Iris characteristics ( 21835309)
- Reticulocyte fraction of red cells ( 27863252)
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Interacting Genes |
115 interacting genes:
ANKIB1
AREL1
ARIH1
ARIH2
ATXN3
BRAF
BRAP
BRCA1
CBL
CBLB
CBLC
CCNB1IP1
CDC42
CDKN1B
CUL9
DTX3
FBXO2
FOS
HACE1
HECTD1
HECTD2
HECTD4
HECW1
HECW2
HERC1
HERC2
HERC3
HERC4
HERC6
HSPA4
HUWE1
IRF2BP1
ITCH
KSR1
LIG4
LTN1
MAP2K1
MAPK6
MDM2
MEX3A
MEX3C
MID1
MKRN3
MUL1
MYCBP2
NEDD4
NEDD4L
NFKBIA
NR3C1
NRAS
PIAS1
PIAS2
PJA1
POLR2A
PRKN
PTEN
RAF1
RBCK1
RBX1
RC3H1
RELA
RNF103
RNF113B
RNF114
RNF125
RNF14
RNF144A
RNF144B
RNF150
RNF168
RNF170
RNF182
RNF19A
RNF19B
RNF2
RNF20
RNF213
RNF216
RNF220
RNF31
RNF7
RTF2
SMAD4
SMAD7
SMURF1
SMURF2
SPOP
STUB1
TP53
TRAF6
TRAF7
TRIM21
TRIM23
TRIM25
TRIM28
TRIM31
TRIM39
TRIM55
TRIP12
UBA1
UBA5
UBA6
UBA7
UBASH3A
UBC
UBE3A
UBE3C
UBOX5
UBR4
UBR5
VPS11
WIPI2
WWP1
WWP2
YWHAQ
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12 interacting genes:
BAK1
EP300
LAPTM5
PKM
RAF1
RNF11
SOX9
UBC
UBE2D2
UBE2D3
UBE2L3
UBE2S
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Entrez ID |
7332 |
8925 |
HPRD ID |
04762 |
06894 |
Ensembl ID |
ENSG00000185651
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ENSG00000103657
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Uniprot IDs |
A0A024R1A4
P68036
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A0A024R5W0
Q15751
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PDB IDs |
1C4Z
1FBV
3SQV
3SY2
4Q5E
4Q5H
5HPT
5TTE
5UDH
6CP2
6DJW
6DJX
6N13
6XXU
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4O2W
4QT6
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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