Description |
ubiquitin conjugating enzyme E2 L3 |
Raf-1 proto-oncogene, serine/threonine kinase |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Asthma ( 32296059)
- Cardiac hypertrophy ( 21348951)
- Carotid intima media thickness x smoking interaction ( 32117412)
- Cholesterol, total ( 24097068 20686565)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
- HDL cholesterol levels ( 32203549)
- Total cholesterol levels ( 28334899)
- Waist-to-hip ratio adjusted for BMI ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
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Interacting Genes |
115 interacting genes:
ANKIB1
AREL1
ARIH1
ARIH2
ATXN3
BRAF
BRAP
BRCA1
CBL
CBLB
CBLC
CCNB1IP1
CDC42
CDKN1B
CUL9
DTX3
FBXO2
FOS
HACE1
HECTD1
HECTD2
HECTD4
HECW1
HECW2
HERC1
HERC2
HERC3
HERC4
HERC6
HSPA4
HUWE1
IRF2BP1
ITCH
KSR1
LIG4
LTN1
MAP2K1
MAPK6
MDM2
MEX3A
MEX3C
MID1
MKRN3
MUL1
MYCBP2
NEDD4
NEDD4L
NFKBIA
NR3C1
NRAS
PIAS1
PIAS2
PJA1
POLR2A
PRKN
PTEN
RAF1
RBCK1
RBX1
RC3H1
RELA
RNF103
RNF113B
RNF114
RNF125
RNF14
RNF144A
RNF144B
RNF150
RNF168
RNF170
RNF182
RNF19A
RNF19B
RNF2
RNF20
RNF213
RNF216
RNF220
RNF31
RNF7
RTF2
SMAD4
SMAD7
SMURF1
SMURF2
SPOP
STUB1
TP53
TRAF6
TRAF7
TRIM21
TRIM23
TRIM25
TRIM28
TRIM31
TRIM39
TRIM55
TRIP12
UBA1
UBA5
UBA6
UBA7
UBASH3A
UBC
UBE3A
UBE3C
UBOX5
UBR4
UBR5
VPS11
WIPI2
WWP1
WWP2
YWHAQ
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160 interacting genes:
ABCB5
ADCY6
AGTR1
AKT1
AR
ARNT
ARRB2
BAD
BAG1
BCL2
BCL2L1
BCL6
BECN1
BIRC2
BIRC3
BRAF
CASZ1
CBLC
CCND2
CCT3
CD44
CDC25A
CDC37
CDK4
CDK6
CDKN2A
CDKN2B
CDKN2C
CFLAR
CNKSR1
COPS3
COPS7A
CPS1
DCAF8
DMPK
EFEMP1
EGFR
EPHA2
ERBB2
ERBIN
FGFR4
FYCO1
FYN
GLIS2
GNB2
GNG4
GRB10
GRM1
HERC1
HGF
HRAS
HSP90AA1
HSPA4
HSPA8
IL2RB
INSR
INTS10
JAK1
JAK2
KEAP1
KRAS
KRT18
KRT8
KSR1
KSR2
LATS2
LCK
LOX
LRPAP1
MAP2K1
MAP2K2
MAP2K3
MAP2K5
MAP2K6
MAP3K1
MAP3K5
MAPK1
MAPK3
MAPK7
MAPK8
MAPK8IP3
MBP
MET
MRAS
MRC2
MYBPC1
MYC
NEDD4
NF1
NF2
NPLOC4
NR3C1
NRAS
NUDT14
OIP5
PACSIN3
PAK1
PAK2
PAK3
PBK
PDGFRA
PDGFRB
PDLIM2
PEBP1
PEBP4
PEX5L
PHB
PHKA2
PIN1
PKM
PPP1CC
PPP2CB
PRKAA1
PRKACA
PRKAR1A
PRKCA
PRKCD
PRKCE
PRKCZ
PRKG1
PRPF6
PURA
RANBP9
RAP1A
RAP2A
RASD2
RASSF1
RB1
RBBP8
RBL2
RFXANK
RHEB
RRAS
RRAS2
RSU1
SHOC2
SPRY2
SPRY4
SRC
STK26
STK3
STUB1
TBXA2R
TEAD2
TERT
TIMM50
TMEM70
TSC22D3
UBE2D2
UBE2L3
VAV1
VDAC1
XIAP
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
YY1
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Entrez ID |
7332 |
5894 |
HPRD ID |
04762 |
01265 |
Ensembl ID |
ENSG00000185651
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ENSG00000132155
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Uniprot IDs |
A0A024R1A4
P68036
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A0A0S2Z4L5
L7RRS6
P04049
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PDB IDs |
1C4Z
1FBV
3SQV
3SY2
4Q5E
4Q5H
5HPT
5TTE
5UDH
6CP2
6DJW
6DJX
6N13
6XXU
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1C1Y
1FAQ
1FAR
1GUA
1RFA
3CU8
3IQJ
3IQU
3IQV
3KUC
3KUD
3NKX
3O8I
3OMV
4FJ3
4G0N
4G3X
4IEA
4IHL
6NTC
6NTD
6PTS
6PTW
7JHP
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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