TNNI3 and RASSF10

Data Source:
BioGRID (two hybrid)

		TNNI3	RASSF10
Description		troponin I3, cardiac type	Ras association domain family member 10
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex Sarcomere Cardiac Myofibril Cardiac Troponin Complex	Spindle Pole Microtubule Organizing Center Cytosol
	Molecular Function	Actin Binding Protein Binding Calcium Channel Inhibitor Activity Protein Kinase Binding Protein Domain Specific Binding Troponin C Binding Troponin T Binding Metal Ion Binding Calcium-dependent Protein Binding Actin Filament Binding	Protein Binding
	Biological Process	Vasculogenesis Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Skeletal Muscle Contraction Cellular Calcium Ion Homeostasis Muscle Contraction Heart Development Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Muscle Filament Sliding Negative Regulation Of ATPase Activity Ventricular Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction	Signal Transduction Positive Regulation Of Neurogenesis Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		Striated Muscle Contraction Ion homeostasis
Drugs		N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide
Diseases		Hypertrophic cardiomyopathy (HCM)
GWAS		Platelet count ( 32888494)	Coronary artery disease ( 32469254) Empathy quotient ( 29527006) Obesity-related traits ( 23251661)
Interacting Genes		19 interacting genes: ACTA1 HSPB2 LYST MST1 PAPPA PKD2 PKD2L1 PRKCA PSMC5 RASSF10 RCAN3 SOX4 TNNC1 TNNC2 TNNI3K TNNT1 TNNT2 TRIM55 TRIM63	23 interacting genes: ATP6V1E2 CBY1 CCDC116 CCDC183 CEP57 CEP70 EGFL7 EIF1AD FAM110A FAM171A1 GADD45G GNG13 GOLGA6L9 LDOC1 MAGEA6 NXT2 SMG9 SMU1 TEAD4 TNNI3 TP53BP2 TRIM54 WNT11
Entrez ID		7137	644943
HPRD ID		11769	19177
Ensembl ID		ENSG00000129991	ENSG00000189431
Uniprot IDs		P19429 Q6FGX2	A6NK89
PDB IDs		1J1D 1J1E 1LXF 1MXL 1OZS 2KGB 2KRD 2L1R 2MZP 2N7L 4Y99 5VLN 5W88 5WCL 6KN7 6KN8 6MV3 7JGI
Enriched GO Terms of Interacting Partners?
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