TFAP2A and WWP1

  • Data Source:
  • HPRD (in vitro)

TFAP2A

WWP1

Description transcription factor AP-2 alpha WW domain containing E3 ubiquitin protein ligase 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Breast cancer in BRCA2 mutation carriers ( 23544012)
  • Glucose homeostasis traits ( 25524916)
  • Iron status biomarkers (ferritin levels) ( 28334935)
  • Metabolite levels ( 23823483)
  • Ovarian cancer ( 30557369)
  • Refractive error ( 32231278)
  • Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
  • Zinc levels ( 26025379)
  • Estimated glomerular filtration rate ( 31152163)
Interacting Genes 38 interacting genes: APC CASP1 CASP3 CASP6 CITED2 CITED4 CLTC CSNK2A1 CSNK2B CTNNB1 DEK EP300 EPN1 EPN2 EPS15 GSTO2 HIP1 INCA1 KCTD15 LDLRAP1 MAGI1 MKRN3 MYC NFKB1 NPM1 PPARG PRKAA2 PRKD1 RB1 SRA1 SUMO4 SYT1 TP53 UBE2I VEGFA WWP1 WWP2 YBX1 55 interacting genes: ARRDC1 ARRDC2 ARRDC3 ASH2L ATN1 CLCN5 CPSF6 DAG1 DAZAP2 DIDO1 EWSR1 FAM189A2 FBXL18 HSPB1 IKBKG IL2RG IL6R KLF2 KLF5 LAPTM5 LATS1 LNX1 LZTR1 MACROH2A2 MIR19A MIR19B1 NFE2 NOTCH1 PCBD1 PHF20L1 PRKAA2 PYGM RASA1 RNF11 RTN4 RUNX1 SCNN1A SFTPC SMAD3 SMAD5 STAT6 TFAP2A TGIF1 TP53BP2 TRAF4 UBC UBE2D1 UBE2D2 UBE2D3 UBE2L3 WASL WBP1 WBP2 YWHAQ ZNF638
Entrez ID 7020 11059
HPRD ID 00128 03811
Ensembl ID ENSG00000137203 ENSG00000123124
Uniprot IDs P05549 Q9H0M0
PDB IDs 1ND7 2OP7 5HPS 5HPT 6J1X 6J1Y
Enriched GO Terms of Interacting Partners?
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