VPS72 and HMBOX1

Data Source:
BioGRID (two hybrid)

		VPS72	HMBOX1
Description		vacuolar protein sorting 72 homolog	homeobox containing 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck Protein-containing Complex	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body
	Molecular Function	DNA Binding Protein Binding Histone Binding	Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Somatic Stem Cell Population Maintenance Histone Exchange	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Interacting Genes		9 interacting genes: CALCOCO2 CCDC85B EWSR1 HMBOX1 HSF2BP MDFI PRMT1 STK11 TET2	100 interacting genes: ABITRAM AEBP2 ANKRD36 APP ASB7 ATP5PO BAZ2B BEND7 BRD1 BYSL C8orf33 CARD9 CBX8 CCDC187 CCNG1 CDC7 CDCA8 CDK18 DAB1 DNTTIP1 DYNLL1 DYNLL2 ENKD1 ENTPD2 FAM13C FAM161A FAM217B FAM74A4 FAM90A1 FARS2 FGF11 FNDC11 FRMD6 FXR2 GAS2L2 GNL3L GSC2 INO80B IPO13 KAT5 KIF9 LMO1 LMO3 LNX1 MAGEH1 MCRS1 MEOX1 MEOX2 MFAP1 MORF4L1 MORF4L2 MRPL11 MRPL28 PAX5 PAX6 PIAS2 PICK1 PIP4K2B PKD1P1 POLDIP3 POLL PRKAA1 PRKAA2 PRPF18 RBMY2FP RCOR3 REEP6 RPL9 RPS25 SAP30L SCNM1 SDCBP SFR1 SH2D4A SNRPB2 SNW1 SYT6 TBP TCEA2 TCEANC TSGA10IP TUFM U2AF2 UBA6 UBE2I UBE2Z VAX1 VPS72 WT1 ZBTB24 ZBTB26 ZFYVE26 ZMAT2 ZMYM5 ZNF250 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688
Entrez ID		6944	79618
HPRD ID		02791	07964
Ensembl ID		ENSG00000163159	ENSG00000147421
Uniprot IDs		Q15906	D3DSU2 Q6NT76
PDB IDs		5FUG	2CUF 4J19
Enriched GO Terms of Interacting Partners?
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