ELOA and REXO1

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		ELOA	REXO1
Description		elongin A	RNA exonuclease 1 homolog
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Elongin Complex Site Of DNA Damage	Nucleus Nucleoplasm Nuclear Body
	Molecular Function	Protein Binding	Nucleic Acid Binding Exonuclease Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter	Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways		Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Body mass index ( 29273807) Essential hypertension (time to event) ( 32589924) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		56 interacting genes: AXIN2 BACH2 BRCA1 CBY2 CCDC57 CDR2L CEP57L1 CEP70 CNTROB CUL5 ELOB ERCC6 EVI5 FAM9B FCHO1 FXR1 GMCL1 GOLGA6A GRIPAP1 HIVEP1 HOMEZ JAKMIP2 KANK2 KLHL2 KRT40 KRTAP10-3 KXD1 LMNA LZTS1 MCC MDFI MED21 MID1 MID2 NAB2 NACC1 NAF1 NFKBID NINL PER2 PLK4 POLR2A PPFIA1 PRDM6 PRMT5 RABEP1 RAD54B RAP1A REXO1 SIRPA SPECC1L TNIP1 TP53BP2 TRIM37 TRIM54 ZNF792	4 interacting genes: ELOA PAFAH1B2 RLIM TCEA1
Entrez ID		6924	57455
HPRD ID		02873	15478
Ensembl ID		ENSG00000011007	ENSG00000079313
Uniprot IDs		Q14241	Q8N1G1
PDB IDs		4HFX
Enriched GO Terms of Interacting Partners?
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