REXO1 and TCEA1

Data Source:
HPRD (in vitro)

		REXO1	TCEA1
Description		RNA exonuclease 1 homolog	transcription elongation factor A1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body	Nucleoplasm Transcription Factor TFIID Complex Nucleolus
	Molecular Function	Nucleic Acid Binding Exonuclease Activity	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Nucleic Acid Phosphodiester Bond Hydrolysis	Transcription-coupled Nucleotide-excision Repair Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Exoribonuclease Activity
Pathways			Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Body mass index ( 29273807) Essential hypertension (time to event) ( 32589924) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Urinary albumin-to-creatinine ratio ( 26631737)
Interacting Genes		4 interacting genes: ELOA PAFAH1B2 RLIM TCEA1	18 interacting genes: APP CDC73 CDK7 CIR1 CTDP1 CTR9 EAF2 GPKOW GTF2E1 GTF2F2 IWS1 LEO1 PAF1 POLR2A REXO1 RTF1 UBR5 WDR61
Entrez ID		57455	6917
HPRD ID		15478	03252
Ensembl ID		ENSG00000079313	ENSG00000187735
Uniprot IDs		Q8N1G1	A0A384MTX4 B7Z4W0 P23193
PDB IDs			1TFI 3NDQ 5IY6 5IY7 5IY8 5IYA 5IYB 5IYC 6O9L
Enriched GO Terms of Interacting Partners?
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