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TAZ and LATS1
Data Source:
BioGRID
(unspecified method)
TAZ
LATS1
Description
tafazzin
large tumor suppressor kinase 1
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Inner Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Spindle Pole
Nucleus
Microtubule Organizing Center
Cytosol
Midbody
Molecular Function
1-acylglycerol-3-phosphate O-acyltransferase Activity
O-acyltransferase Activity
1-acylglycerophosphocholine O-acyltransferase Activity
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Protein Kinase Binding
Estrogen Receptor Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Muscle Contraction
Inner Mitochondrial Membrane Organization
Heart Development
Skeletal Muscle Tissue Development
Hemopoiesis
Cardiolipin Biosynthetic Process
Mitochondrial Respiratory Chain Complex I Assembly
Cardiolipin Acyl-chain Remodeling
Cristae Formation
Mitochondrial ATP Synthesis Coupled Electron Transport
Cardiac Muscle Tissue Development
Cardiac Muscle Contraction
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Sister Chromatid Segregation
Inner Cell Mass Cell Fate Commitment
Inner Cell Mass Cellular Morphogenesis
Protein Phosphorylation
Hormone-mediated Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Peptidyl-serine Phosphorylation
Keratinocyte Differentiation
Regulation Of Actin Filament Polymerization
Positive Regulation Of Peptidyl-serine Phosphorylation
Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Cellular Protein Localization
Hippo Signaling
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Organ Growth
Cytoplasmic Sequestering Of Protein
Cell Division
Mammary Gland Epithelial Cell Differentiation
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways
Mitochondrial protein import
Mitochondrial protein import
Acyl chain remodeling of CL
Signaling by Hippo
Drugs
Fostamatinib
Diseases
3-Methylglutaconic aciduria (MGCA)
Barth syndrome (BTHS)
Dilated cardiomyopathy (DCM)
GWAS
Brain morphology (MOSTest) (
32665545
)
Nicotine dependence and major depression (severity of comorbidity) (
30287806
)
Subcortical volume (MOSTest) (
32665545
)
Testicular germ cell tumor (
28604728
)
Interacting Genes
9 interacting genes:
BTRC
CHGB
CSNK1E
GSK3B
LATS1
LATS2
RUNX1
SLC9A3R2
YWHAE
48 interacting genes:
ALPP
APP
ARPC3
AURKB
CAV1
CBY2
CDC26
CDK1
CEP76
EIF4EBP1
FOXL2
FSD2
GOLGA2
KRT31
LDOC1
LIMK1
LRRK2
MAGI3
MOAP1
MOB3A
MOB3B
MOB3C
MOB4
NEDD4
NF2
NUAK1
NUAK2
OSTF1
PABPN1
PPM1F
PPP1R11
PPP6R3
PTEN
RAC1
SMURF1
SMURF2
SSX2IP
STK3
STK4
TAZ
TFIP11
TRAF1
UBE2I
UBQLN2
WWOX
WWP1
WWTR1
ZYX
Entrez ID
6901
9113
HPRD ID
02316
09147
Ensembl ID
ENSG00000102125
ENSG00000131023
Uniprot IDs
A0A0S2Z4E6
A0A0S2Z4F4
A0A0S2Z4K0
A0A0S2Z4K9
A0A494C0C5
A0A499FJ53
A6XNE1
Q16635
O95835
PDB IDs
4ZRK
5B5W
5BRK
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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