TAZ and CSNK1E

Data Source:
BioGRID (affinity chromatography technology, enzymatic study)

		TAZ	CSNK1E
Description		tafazzin	casein kinase 1 epsilon
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane Mitochondrial Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity O-acyltransferase Activity 1-acylglycerophosphocholine O-acyltransferase Activity	RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Muscle Contraction Inner Mitochondrial Membrane Organization Heart Development Skeletal Muscle Tissue Development Hemopoiesis Cardiolipin Biosynthetic Process Mitochondrial Respiratory Chain Complex I Assembly Cardiolipin Acyl-chain Remodeling Cristae Formation Mitochondrial ATP Synthesis Coupled Electron Transport Cardiac Muscle Tissue Development Cardiac Muscle Contraction	G2/M Transition Of Mitotic Cell Cycle DNA Repair Protein Phosphorylation Endocytosis Signal Transduction Regulation Of G2/M Transition Of Mitotic Cell Cycle Wnt Signaling Pathway Peptidyl-serine Phosphorylation Negative Regulation Of Protein Binding Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Ciliary Basal Body-plasma Membrane Docking Regulation Of Cellular Protein Localization Positive Regulation Of Wnt-mediated Midbrain Dopaminergic Neuron Differentiation Positive Regulation Of Non-canonical Wnt Signaling Pathway
Pathways		Mitochondrial protein import Mitochondrial protein import Acyl chain remodeling of CL	WNT mediated activation of DVL Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Circadian Clock Anchoring of the basal body to the plasma membrane Major pathway of rRNA processing in the nucleolus and cytosol AURKA Activation by TPX2
Drugs			Seliciclib
Diseases		3-Methylglutaconic aciduria (MGCA) Barth syndrome (BTHS) Dilated cardiomyopathy (DCM)
GWAS			Keratoconus ( 31855235)
Interacting Genes		9 interacting genes: BTRC CHGB CSNK1E GSK3B LATS1 LATS2 RUNX1 SLC9A3R2 YWHAE	55 interacting genes: AKAP9 ANKRD6 APC APP ARHGEF1 ARNTL AXIN1 AXIN2 BBS10 BHLHE41 BID CADM4 CLOCK CRY1 CSNK2B DELEC1 DVL1 DVL2 DVL3 ENTR1 FAM110A FAM110C FAM83D FBP1 FBXO7 FBXW11 GTF3C1 HES1 KAT7 MCC NCOA3 NR1D2 PER1 PER2 PER3 PPP1CA PPP1CC PPP1R14A PPP2R5D PPP2R5E PTPRD RAD54B RBX1 RORA RORC SOCS3 TAOK1 TAZ TNS2 TRAF3 TRIM3 WDCP ZMYND8 ZNF227 ZNF618
Entrez ID		6901	1454
HPRD ID		02316	02919
Ensembl ID		ENSG00000102125	ENSG00000213923
Uniprot IDs		A0A0S2Z4E6 A0A0S2Z4F4 A0A0S2Z4K0 A0A0S2Z4K9 A0A494C0C5 A0A499FJ53 A6XNE1 Q16635	P49674 Q5U045
PDB IDs			4HNI 4HOK
Enriched GO Terms of Interacting Partners?
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