SVIL and KIF22

Data Source:
BioGRID (two hybrid)

		SVIL	KIF22
Description		supervillin	kinesin family member 22
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GO Annotations	Cellular Component	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere	Kinetochore Chromatin Nucleus Cytosol Kinesin Complex Microtubule Nuclear Speck Mitotic Spindle
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding	DNA Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Skeletal Muscle Tissue Development Actin Polymerization Or Depolymerization Positive Regulation Of Cytokinesis Actin Filament Severing Barbed-end Actin Filament Capping	Mitotic Cell Cycle DNA Repair Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Sister Chromatid Cohesion Mitotic Metaphase Plate Congression Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Metaphase Plate Congression
Pathways			MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Bone fracture in osteoporosis ( 28580392) Estimated glomerular filtration rate ( 31152163) Lung function (FEV1/FVC) ( 28166213) Metabolite levels ( 23823483) Neurofibrillary tangles ( 25188341) Normalized brain volume ( 19010793) Platelet thrombus formation ( 22550155) Plateletcrit ( 32888494)	Red blood cell traits ( 23222517)
Interacting Genes		35 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG	6 interacting genes: ATXN1 GDF9 IMMT PJA1 SIAH1 SVIL
Entrez ID		6840	3835
HPRD ID		04992	04445
Ensembl ID		ENSG00000197321	ENSG00000079616
Uniprot IDs		A0A6I8PIX7 O95425 Q569J5	A0A024R632 B7Z9T5 Q14807
PDB IDs		2K6M 2K6N	2EDU 6NJE
Enriched GO Terms of Interacting Partners?
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