SSTR5 and SST

Data Source:
HPRD (in vivo)

		SSTR5	SST
Description		somatostatin receptor 5	somatostatin
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection	Extracellular Region Extracellular Space Neuronal Cell Body Synapse
	Molecular Function	G Protein-coupled Receptor Activity Somatostatin Receptor Activity Peptide Binding Neuropeptide Binding	Hormone Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Negative Regulation Of Cell Population Proliferation Positive Regulation Of Cytokinesis Somatostatin Signaling Pathway Glucose Homeostasis Regulation Of Insulin Secretion Cellular Response To Glucocorticoid Stimulus	Hyperosmotic Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Chemical Synaptic Transmission Response To Nutrient Digestion Negative Regulation Of Cell Population Proliferation Hormone-mediated Apoptotic Signaling Pathway Response To Heat Response To Acidic PH Regulation Of Cell Migration Response To Drug Response To Amino Acid Response To Steroid Hormone
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events MECP2 regulates transcription of neuronal ligands
Drugs		Vapreotide Pasireotide Lanreotide Somatostatin Lutetium Lu 177 dotatate Edotreotide gallium Ga-68
Diseases
GWAS		Logical memory (immediate recall) in normal cognition ( 29274321) Polycystic ovary syndrome ( 25574032)	Pursuit maintenance gain ( 29064472) Skin pigmentation ( 28300201)
Interacting Genes		9 interacting genes: ADCY10 CNR1 CORT DRD2 GOPC PDZK1 PEX5 SST SSTR1	6 interacting genes: PDIA2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
Entrez ID		6755	6750
HPRD ID		01677	08920
Ensembl ID		ENSG00000162009	ENSG00000157005
Uniprot IDs		P35346	P61278
PDB IDs			1P2W 2MI1
Enriched GO Terms of Interacting Partners?
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