SST and SSTR2

Data Source:
HPRD (in vivo)

		SST	SSTR2
Description		somatostatin	somatostatin receptor 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Neuronal Cell Body Synapse	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	Hormone Activity Protein Binding	G Protein-coupled Receptor Activity Somatostatin Receptor Activity Protein Binding PDZ Domain Binding Peptide Binding Neuropeptide Binding
	Biological Process	Hyperosmotic Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Chemical Synaptic Transmission Response To Nutrient Digestion Negative Regulation Of Cell Population Proliferation Hormone-mediated Apoptotic Signaling Pathway Response To Heat Response To Acidic PH Regulation Of Cell Migration Response To Drug Response To Amino Acid Response To Steroid Hormone	Regulation Of Muscle Contraction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Spermatogenesis Negative Regulation Of Cell Population Proliferation Cerebellum Development Peristalsis Forebrain Development Somatostatin Signaling Pathway Response To Starvation Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events MECP2 regulates transcription of neuronal ligands	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs			Vapreotide Pasireotide Lanreotide Somatostatin Dotatate gallium Ga-68 Lutetium Lu 177 dotatate Edotreotide gallium Ga-68 Copper oxodotreotide Cu-64
Diseases
GWAS		Pursuit maintenance gain ( 29064472) Skin pigmentation ( 28300201)	Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: PDIA2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5	10 interacting genes: APP CORT DRD2 GNA14 GNAI1 PIK3R1 PTPN6 SHANK1 SHANK2 SST
Entrez ID		6750	6752
HPRD ID		08920	01674
Ensembl ID		ENSG00000157005	ENSG00000180616
Uniprot IDs		P61278	P30874
PDB IDs		1P2W 2MI1
Enriched GO Terms of Interacting Partners?
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