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SPTBN2 and UNC13B
Data Source:
HPRD
(two hybrid)
SPTBN2
UNC13B
Description
spectrin beta, non-erythrocytic 2
unc-13 homolog B
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Cytosol
Spectrin
Apical Plasma Membrane
Neuronal Cell Body
Parallel Fiber To Purkinje Cell Synapse
Presynapse
Glutamatergic Synapse
Postsynaptic Spectrin-associated Cytoskeleton
Golgi Apparatus
Cytosol
Plasma Membrane
Membrane
Synaptic Vesicle Membrane
Neuromuscular Junction
Presynaptic Membrane
Terminal Bouton
Presynaptic Active Zone
Presynaptic Active Zone Cytoplasmic Component
Molecular Function
Actin Binding
Structural Constituent Of Cytoskeleton
Phospholipid Binding
Cadherin Binding
Structural Constituent Of Synapse
Calcium Ion Binding
Protein Binding
Calmodulin Binding
Phospholipid Binding
Syntaxin-1 Binding
Diacylglycerol Binding
GTP-dependent Protein Binding
Small GTPase Binding
Biological Process
MAPK Cascade
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Cytoskeleton Organization
Axon Guidance
Synapse Assembly
Vesicle-mediated Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Cerebellar Purkinje Cell Layer Morphogenesis
Adult Behavior
Multicellular Organism Growth
Actin Filament Capping
Postsynapse Organization
Chemical Synaptic Transmission
Neurotransmitter Secretion
Neuromuscular Junction Development
Positive Regulation Of Synaptic Vesicle Priming
Glutamate Secretion
Synaptic Vesicle Docking
Synaptic Vesicle Priming
Synaptic Vesicle Maturation
Synaptic Transmission, Glutamatergic
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Positive Regulation Of Protein Secretion
Acrosomal Vesicle Exocytosis
Dense Core Granule Priming
Cellular Response To Glucose Stimulus
Positive Regulation Of Inhibitory Postsynaptic Potential
Neuronal Dense Core Vesicle Exocytosis
Presynaptic Dense Core Vesicle Exocytosis
Pathways
MHC class II antigen presentation
NCAM signaling for neurite out-growth
NCAM signaling for neurite out-growth
Interaction between L1 and Ankyrins
Interaction between L1 and Ankyrins
RAF/MAP kinase cascade
COPI-mediated anterograde transport
Serotonin Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Drugs
Diseases
Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS
Bipolar disorder (
28115744
21926972
31043756
)
Parkinson's disease (
21812969
)
Interacting Genes
11 interacting genes:
ACTA1
ACTB
ACTR1A
ADRB2
APC
CELSR3
DCTN1
MINK1
SPTA1
SPTAN1
UNC13B
11 interacting genes:
CLK1
DOC2A
DOC2B
PDCL2
RIMS1
RPH3AL
SPTBN2
STX1A
STX1B
STX2
TOE1
Entrez ID
6712
10497
HPRD ID
05404
05785
Ensembl ID
ENSG00000173898
ENSG00000198722
Uniprot IDs
O15020
O14795
Q4LE73
PDB IDs
1WJM
1WYQ
6ANU
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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