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UNC13B and STX1B
Data Source:
BioGRID
(two hybrid, biochemical)
UNC13B
STX1B
Description
unc-13 homolog B
syntaxin 1B
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
Cytosol
Plasma Membrane
Membrane
Synaptic Vesicle Membrane
Neuromuscular Junction
Presynaptic Membrane
Terminal Bouton
Presynaptic Active Zone
Presynaptic Active Zone Cytoplasmic Component
Nucleus
Microtubule Organizing Center
Spindle
Cytosol
Plasma Membrane
Synaptic Vesicle
Endomembrane System
Membrane
Integral Component Of Membrane
Axon
SNARE Complex
Neuromuscular Junction
Presynaptic Active Zone Membrane
Molecular Function
Calcium Ion Binding
Protein Binding
Calmodulin Binding
Phospholipid Binding
Syntaxin-1 Binding
Diacylglycerol Binding
GTP-dependent Protein Binding
Small GTPase Binding
SNARE Binding
Signaling Receptor Binding
SNAP Receptor Activity
Protein Binding
Protein Kinase Binding
Protein Domain Specific Binding
Biological Process
Chemical Synaptic Transmission
Neurotransmitter Secretion
Neuromuscular Junction Development
Positive Regulation Of Synaptic Vesicle Priming
Glutamate Secretion
Synaptic Vesicle Docking
Synaptic Vesicle Priming
Synaptic Vesicle Maturation
Synaptic Transmission, Glutamatergic
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Positive Regulation Of Protein Secretion
Acrosomal Vesicle Exocytosis
Dense Core Granule Priming
Cellular Response To Glucose Stimulus
Positive Regulation Of Inhibitory Postsynaptic Potential
Neuronal Dense Core Vesicle Exocytosis
Presynaptic Dense Core Vesicle Exocytosis
Positive Regulation Of Neurotransmitter Secretion
Intracellular Protein Transport
Exocytosis
Vesicle Docking Involved In Exocytosis
Vesicle Fusion
Regulation Of Gene Expression
Regulation Of Synaptic Vesicle Priming
Negative Regulation Of Neuron Projection Development
Synaptic Vesicle Docking
Regulation Of Exocytosis
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Vesicle Docking
Calcium Ion-regulated Exocytosis Of Neurotransmitter
Regulation Of Synaptic Activity
Spontaneous Neurotransmitter Secretion
Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane
Negative Regulation Of Synaptic Vesicle Recycling
Positive Regulation Of Spontaneous Neurotransmitter Secretion
Negative Regulation Of Macropinocytosis
Positive Regulation Of Excitatory Postsynaptic Potential
Pathways
Serotonin Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Toxicity of botulinum toxin type C (botC)
LGI-ADAM interactions
Drugs
Diseases
GWAS
Parkinson's disease (
21812969
)
Adult body size (
32376654
)
Body mass index (
31453325
)
Body mass index variance (
31453325
)
Dementia with Lewy bodies (
29263008
)
Hip circumference (
31453325
)
Hip circumference variance (
31453325
)
Juvenile myoclonic epilepsy (
30531953
)
Low density lipoprotein cholesterol levels (
32154731
)
Parkinson's disease (
25064009
32201043
)
Psoriasis (
25574825
)
Response to metformin (IC50) (
28173075
)
Waist circumference (
31453325
)
Waist circumference variance (
31453325
)
Interacting Genes
11 interacting genes:
CLK1
DOC2A
DOC2B
PDCL2
RIMS1
RPH3AL
SPTBN2
STX1A
STX1B
STX2
TOE1
29 interacting genes:
ABHD16A
ACBD5
AQP6
BET1
EBP
ERGIC3
FAM161B
FAM209A
FAM81A
FBXO28
FGA
GJA8
GPR152
KCNN4
MMGT1
NAPB
SNAP23
SNAP29
SNAP47
STX2
STX4
STXBP1
TMEM167B
TXLNA
UBE2I
UNC13B
VAMP1
VAMP2
VAMP5
Entrez ID
10497
112755
HPRD ID
05785
18126
Ensembl ID
ENSG00000198722
ENSG00000099365
Uniprot IDs
O14795
Q4LE73
P61266
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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