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SPTAN1 and PTOV1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
SPTAN1
PTOV1
Description
spectrin alpha, non-erythrocytic 1
PTOV1 extended AT-hook containing adaptor protein
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Cytosol
Spectrin
Microtubule Cytoskeleton
Membrane
Specific Granule Lumen
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Extracellular Vesicle
Tertiary Granule Lumen
Nucleoplasm
Transcription Regulator Complex
Plasma Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
Actin Binding
Structural Constituent Of Cytoskeleton
Calcium Ion Binding
Protein Binding
Calmodulin Binding
Cadherin Binding
Biological Process
MAPK Cascade
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Cytoskeleton Organization
Axon Guidance
Neutrophil Degranulation
Actin Filament Capping
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Caspase-mediated cleavage of cytoskeletal proteins
Nephrin family interactions
NCAM signaling for neurite out-growth
NCAM signaling for neurite out-growth
Interaction between L1 and Ankyrins
Interaction between L1 and Ankyrins
RAF/MAP kinase cascade
Neutrophil degranulation
COPI-mediated anterograde transport
Drugs
Diseases
Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS
Axial length (
24144296
)
Body mass index (
26426971
)
Interacting Genes
56 interacting genes:
ABI1
ABL1
ACP1
ACTA1
ACTB
AKIP1
ANK1
CAPN1
CASP3
CASP7
CEP63
CTNNA1
DDX24
DES
EPB41
EPB41L2
EPB42
ERCC4
EVL
EXOC1
FANCA
FANCC
GAP43
GRIA2
GRIN1
GRIN2A
GRIN2B
GRIN2D
KALRN
KARS1
MAPK6
NEFL
PDE4D
PIN4
PLEC
PLEKHA5
PRKCB
PTEN
PTOV1
SHANK1
SHANK3
SLC9A2
SOS1
SPTB
SPTBN1
SPTBN2
SPTBN4
SRC
STAT1
SUMO2
SYN1
TAF1
TANC1
TES
TSSC4
ZNF333
9 interacting genes:
CCR4
DMTN
HDAC6
PIN1
RACK1
SPTAN1
TMCC2
UBC
USP16
Entrez ID
6709
53635
HPRD ID
01684
17929
Ensembl ID
ENSG00000197694
ENSG00000104960
Uniprot IDs
A0A384P5S9
Q13813
A0A0C4DGR2
Q86YD1
PDB IDs
2FOT
3F31
3FB2
5FW9
5FWB
5FWC
6ZEH
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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