SLC34A1 and YIF1A

Data Source:
HPRD (two hybrid)

		SLC34A1	YIF1A
Description		solute carrier family 34 member 1	Yip1 interacting factor homolog A, membrane trafficking protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endosome Cytosol Plasma Membrane Integral Component Of Plasma Membrane Brush Border Cell Surface Apical Plasma Membrane Nuclear Speck Brush Border Membrane Vesicle Membrane Raft Perinuclear Region Of Cytoplasm Mitotic Spindle	Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus COPII-coated ER To Golgi Transport Vesicle Integral Component Of Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Sodium:phosphate Symporter Activity Protein Binding PDZ Domain Binding Identical Protein Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Ossification Kidney Development Phosphate Ion Transport Glycoprotein Metabolic Process Response To Lead Ion Cellular Phosphate Ion Homeostasis Response To Magnesium Ion Response To Estradiol Response To Vitamin A Phosphate Ion Transmembrane Transport Response To Potassium Ion Indole Metabolic Process Response To Drug Cellular Protein Metabolic Process Sodium-dependent Phosphate Transport Positive Regulation Of Membrane Potential Response To Cadmium Ion Response To Mercury Ion Phosphate Ion Homeostasis Response To Growth Hormone Cellular Response To Metal Ion Cellular Response To Parathyroid Hormone Stimulus Tricarboxylic Acid Metabolic Process Cellular Response To Staurosporine Response To Thyroid Hormone Dentinogenesis Sodium Ion Import Across Plasma Membrane Gentamycin Metabolic Process Arsenate Ion Transmembrane Transport Positive Regulation Of Sodium-dependent Phosphate Transport Positive Regulation Of Phosphate Transmembrane Transport	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport IRE1-mediated Unfolded Protein Response
Pathways		Type II Na+/Pi cotransporters Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1) Surfactant metabolism	XBP1(S) activates chaperone genes
Drugs
Diseases		Nephrolithiasis/osteoporosis, hypophosphatemic
GWAS		Activated partial thromboplastin time ( 22703881) Asthma ( 32296059) Calcium levels ( 24068962) Chronic kidney disease ( 31152163 26831199 20383146) Creatinine levels ( 31015462 28270201 29403010) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 27588450 29403010) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Hematocrit ( 29403010) Inflammatory bowel disease ( 28067908) Kidney stones ( 26272126 31729369) Nephrolithiasis ( 22396660) Phosphorus levels ( 29403010) Red blood cell count ( 29403010) Serum parathyroid hormone levels ( 27927781) Ulcerative colitis ( 28067908) Urinary electrolytes (magnesium/calcium ratio) ( 27915449) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)
Interacting Genes		11 interacting genes: BSPRY FHL2 HPCAL1 HSP90AA1 HSP90AB1 MAST2 PDZK1 PEX19 SLC9A3R1 SLC9A3R2 YIF1A	72 interacting genes: APOA5 AQP6 BNIP2 C4orf3 CD79A CDK2AP2 CERS2 CNRIP1 CST6 EBP ELOVL4 ERGIC3 FAM210B FARS2 FCER1G FFAR2 GAS7 GJA8 GPR37 GPR42 GPX8 HSD17B11 JOSD2 LNPK LSS MARCHF5 MGST3 MIEF2 MLLT1 MMGT1 MSMO1 MTERF3 MYG1 NDRG4 PLEKHF2 PPIF PTGES PTPN9 RBFA REEP2 REEP4 RIC3 RNF144A SCN3B SCN4B SDCBP SEC23IP SLC10A1 SLC34A1 SLC35C2 SNX10 SNX11 SNX2 SYTL2 SYTL5 TIMMDC1 TMEM139 TMEM14B TMEM17 TMEM225B TMEM248 TMEM31 TMX2 VKORC1 VMA21 WDFY2 YIPF4 YIPF5 ZDHHC16 ZDHHC17 ZFYVE21 ZFYVE27
Entrez ID		6569	10897
HPRD ID		08918	06755
Ensembl ID		ENSG00000131183	ENSG00000174851
Uniprot IDs		A0A024R7R9 Q06495 Q7Z725 Q86VN6	A6NGW1 A8K509 O95070
PDB IDs
Enriched GO Terms of Interacting Partners?
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