SLC34A1 and BSPRY

Data Source:
HPRD (two hybrid)

		SLC34A1	BSPRY
Description		solute carrier family 34 member 1	B-box and SPRY domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endosome Cytosol Plasma Membrane Integral Component Of Plasma Membrane Brush Border Cell Surface Apical Plasma Membrane Nuclear Speck Brush Border Membrane Vesicle Membrane Raft Perinuclear Region Of Cytoplasm Mitotic Spindle	Cytoplasm Membrane Cell Leading Edge Perinuclear Region Of Cytoplasm
	Molecular Function	Sodium:phosphate Symporter Activity Protein Binding PDZ Domain Binding Identical Protein Binding Protein-containing Complex Binding	Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ossification Kidney Development Phosphate Ion Transport Glycoprotein Metabolic Process Response To Lead Ion Cellular Phosphate Ion Homeostasis Response To Magnesium Ion Response To Estradiol Response To Vitamin A Phosphate Ion Transmembrane Transport Response To Potassium Ion Indole Metabolic Process Response To Drug Cellular Protein Metabolic Process Sodium-dependent Phosphate Transport Positive Regulation Of Membrane Potential Response To Cadmium Ion Response To Mercury Ion Phosphate Ion Homeostasis Response To Growth Hormone Cellular Response To Metal Ion Cellular Response To Parathyroid Hormone Stimulus Tricarboxylic Acid Metabolic Process Cellular Response To Staurosporine Response To Thyroid Hormone Dentinogenesis Sodium Ion Import Across Plasma Membrane Gentamycin Metabolic Process Arsenate Ion Transmembrane Transport Positive Regulation Of Sodium-dependent Phosphate Transport Positive Regulation Of Phosphate Transmembrane Transport	Calcium Ion Transport Protein Ubiquitination Cellular Response To Leukemia Inhibitory Factor
Pathways		Type II Na+/Pi cotransporters Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1) Surfactant metabolism
Drugs
Diseases		Nephrolithiasis/osteoporosis, hypophosphatemic
GWAS		Activated partial thromboplastin time ( 22703881) Asthma ( 32296059) Calcium levels ( 24068962) Chronic kidney disease ( 31152163 26831199 20383146) Creatinine levels ( 31015462 28270201 29403010) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 27588450 29403010) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Hematocrit ( 29403010) Inflammatory bowel disease ( 28067908) Kidney stones ( 26272126 31729369) Nephrolithiasis ( 22396660) Phosphorus levels ( 29403010) Red blood cell count ( 29403010) Serum parathyroid hormone levels ( 27927781) Ulcerative colitis ( 28067908) Urinary electrolytes (magnesium/calcium ratio) ( 27915449) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Lead levels in blood ( 25820613) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		11 interacting genes: BSPRY FHL2 HPCAL1 HSP90AA1 HSP90AB1 MAST2 PDZK1 PEX19 SLC9A3R1 SLC9A3R2 YIF1A	3 interacting genes: SLC34A1 YWHAZ ZYX
Entrez ID		6569	54836
HPRD ID		08918	16566
Ensembl ID		ENSG00000131183	ENSG00000119411
Uniprot IDs		A0A024R7R9 Q06495 Q7Z725 Q86VN6	Q5W0U4
PDB IDs
Enriched GO Terms of Interacting Partners?
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