CENPH and H2AP

		CENPH	H2AP
Description		centromere protein H	H2A.P histone
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytosol
	Molecular Function	Protein Binding Kinetochore Binding	DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Mitotic Spindle Organization Chromosome Segregation CENP-A Containing Nucleosome Assembly Kinetochore Assembly Kinetochore Organization	Chromatin Silencing
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Interacting Genes		19 interacting genes: ABI2 C1orf216 C8orf58 CCDC146 CENPK DCTN2 ERH H2AP KIF2C LMNB1 MESD MTAP NDC80 NUF2 NUP54 RASSF4 SPAG5 ZNF493 ZSCAN12	10 interacting genes: ATXN1 CENPH CEP44 HTT MAGEB4 MYOG NTAQ1 SEPTIN10 SIX1 ZDHHC17
Entrez ID		64946	25763
HPRD ID		12029	19386
Ensembl ID		ENSG00000153044	ENSG00000187516
Uniprot IDs		A0A0S2Z5T0 Q9H3R5	O75409
PDB IDs
Enriched GO Terms of Interacting Partners?
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