Wiki-Pi

  • About
  • Search
  • Browse
  • People
  • Updates

H2AP and CENPH

  • Data Source:
  • BioGRID (two hybrid)

H2AP

CENPH

Description H2A.P histone centromere protein H
Image No pdb structure No pdb structure
GO Annotations Cellular Component
  • Kinetochore
  • Condensed Chromosome Kinetochore
  • Nucleus
  • Nucleoplasm
  • Chromosome
  • Nucleolus
  • Cytosol
Molecular Function
  • DNA Binding
  • Protein Binding
  • Protein Heterodimerization Activity
  • Protein Binding
  • Kinetochore Binding
Biological Process
  • Chromatin Silencing
  • Mitotic Spindle Organization
  • Chromosome Segregation
  • CENP-A Containing Nucleosome Assembly
  • Kinetochore Assembly
  • Kinetochore Organization
Pathways
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • RHO GTPases Activate Formins
  • Deposition of new CENPA-containing nucleosomes at the centromere
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Interacting Genes 10 interacting genes: ATXN1 CENPH CEP44 HTT MAGEB4 MYOG NTAQ1 SEPTIN10 SIX1 ZDHHC17 19 interacting genes: ABI2 C1orf216 C8orf58 CCDC146 CENPK DCTN2 ERH H2AP KIF2C LMNB1 MESD MTAP NDC80 NUF2 NUP54 RASSF4 SPAG5 ZNF493 ZSCAN12
Entrez ID 25763 64946
HPRD ID 19386 12029
Ensembl ID ENSG00000187516 ENSG00000153044
Uniprot IDs O75409 A0A0S2Z5T0 Q9H3R5
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?

© Madhavi K. Ganapathiraju 2012-2025