TBC1D15 and RAB5C

Data Source:
BioGRID (two hybrid)

		TBC1D15	RAB5C
Description		TBC1 domain family member 15	RAB5C, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm	Lysosomal Membrane Endosome Early Endosome Lipid Droplet Plasma Membrane Endomembrane System Endocytic Vesicle Early Endosome Membrane Azurophil Granule Membrane Melanosome Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Intracellular Protein Transport Regulation Of GTPase Activity Activation Of GTPase Activity Regulation Of Cilium Assembly	Intracellular Protein Transport Endocytosis Regulation Of Endocytosis Neutrophil Degranulation Plasma Membrane To Endosome Transport
Pathways		TBC/RABGAPs	Golgi Associated Vesicle Biogenesis Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Inferior parietal cortex volume ( 31530798) Metabolite levels ( 23823483)	Coronary artery disease ( 29212778) Fibrinogen levels ( 28107422 26561523) Mean corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Vitiligo ( 27723757) vWF and FVIII levels ( 30586737) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: CALCOCO1 CEP63 FIS1 OPTN RAB5A RAB5B RAB5C TAX1BP1 UBC	15 interacting genes: ALS2CL APP APPL2 EEA1 ERBB2 GLP1R HRAS INCA1 RABAC1 RBSN RIN2 RIN3 SGSM3 TBC1D15 TBC1D17
Entrez ID		64786	5878
HPRD ID		15470	04947
Ensembl ID		ENSG00000121749	ENSG00000108774
Uniprot IDs		A8K8E1 Q8TC07	A0A024R1U4 P51148
PDB IDs			4KYI
Enriched GO Terms of Interacting Partners?
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