RAB5C and RBSN

Data Source:
BioGRID (pull down)

		RAB5C	RBSN
Description		RAB5C, member RAS oncogene family	rabenosyn, RAB effector
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GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Lipid Droplet Plasma Membrane Endomembrane System Endocytic Vesicle Early Endosome Membrane Azurophil Granule Membrane Melanosome Extracellular Exosome	Endosome Cytosol Plasma Membrane Endosome Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Protein Binding Zinc Ion Binding
	Biological Process	Intracellular Protein Transport Endocytosis Regulation Of Endocytosis Neutrophil Degranulation Plasma Membrane To Endosome Transport	Blood Coagulation Protein Transport Endosomal Transport Early Endosome To Golgi Transport Golgi To Lysosome Transport Regulation Of Golgi Organization
Pathways		Golgi Associated Vesicle Biogenesis Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Toll Like Receptor 9 (TLR9) Cascade Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Fibrinogen levels ( 28107422 26561523) Mean corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Vitiligo ( 27723757) vWF and FVIII levels ( 30586737) White blood cell count ( 32888494)
Interacting Genes		15 interacting genes: ALS2CL APP APPL2 EEA1 ERBB2 GLP1R HRAS INCA1 RABAC1 RBSN RIN2 RIN3 SGSM3 TBC1D15 TBC1D17	14 interacting genes: AGTR1 DISC1 DNAJC5 DTNBP1 EHD1 EHD2 MAPK14 RAB14 RAB24 RAB2A RAB4A RAB5A RAB5C VPS45
Entrez ID		5878	64145
HPRD ID		04947	15732
Ensembl ID		ENSG00000108774	ENSG00000131381
Uniprot IDs		A0A024R1U4 P51148	A8K5H3 Q9H1K0
PDB IDs		4KYI	1YZM 1Z0J 1Z0K
Enriched GO Terms of Interacting Partners?
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