SHOX and HEMK1

Data Source:
BioGRID (two hybrid)

		SHOX	HEMK1
Description		short stature homeobox	HemK methyltransferase family member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Mitochondrion
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Protein Binding N-methyltransferase Activity Protein Methyltransferase Activity Protein-(glutamine-N5) Methyltransferase Activity
	Biological Process	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	DNA Methylation Protein Methylation
Pathways
Drugs
Diseases		SHOX-related haploinsufficiency disorders, including: Isolated short stature; Langer syndrome; Leri-Weill syndrome
GWAS			Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025) Cocaine dependence ( 31212010) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Height ( 28552196)
Interacting Genes		5 interacting genes: CSNK2A1 GLIS2 HEMK1 IGBP1 NKX2-5	18 interacting genes: AKAP8L ASCL3 CDC23 CHN1 CTAG1A CTAG1B HEATR9 INCA1 KRTAP19-1 MAGED1 PEF1 POU2AF1 PSMB4 SHOX SOHLH1 SPRYD7 TUBGCP5 UBQLN2
Entrez ID		6473	51409
HPRD ID		02430	13645
Ensembl ID		ENSG00000185960	ENSG00000114735
Uniprot IDs		A0A024R385 O15266	A0A140VK98 B2RA37 Q9Y5R4
PDB IDs
Enriched GO Terms of Interacting Partners?
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