HEMK1 and SOHLH1

Data Source:
BioGRID (two hybrid)

		HEMK1	SOHLH1
Description		HemK methyltransferase family member 1	spermatogenesis and oogenesis specific basic helix-loop-helix 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Chromatin Nucleus Cytoplasm
	Molecular Function	DNA Binding Protein Binding N-methyltransferase Activity Protein Methyltransferase Activity Protein-(glutamine-N5) Methyltransferase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	DNA Methylation Protein Methylation	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Spermatogenesis Oocyte Differentiation Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025) Cocaine dependence ( 31212010) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Height ( 28552196)
Interacting Genes		18 interacting genes: AKAP8L ASCL3 CDC23 CHN1 CTAG1A CTAG1B HEATR9 INCA1 KRTAP19-1 MAGED1 PEF1 POU2AF1 PSMB4 SHOX SOHLH1 SPRYD7 TUBGCP5 UBQLN2	26 interacting genes: ACTN3 ARID5A C10orf55 CASP3 CERCAM CTAG1A CTAG1B DTX2 FAM222B HEMK1 IL16 KRTAP19-5 NUP54 OIP5 PEF1 PFDN5 PRKAA2 PSMB4 RUSC1 STH SUOX TENT5B TLE5 TRAF1 USHBP1 ZMYND12
Entrez ID		51409	402381
HPRD ID		13645	16678
Ensembl ID		ENSG00000114735	ENSG00000165643
Uniprot IDs		A0A140VK98 B2RA37 Q9Y5R4	Q5JUK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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