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CLEC7A and UPK2
Data Source:
BioGRID
(two hybrid)
CLEC7A
UPK2
Description
C-type lectin domain containing 7A
uroplakin 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Integral Component Of Plasma Membrane
Apical Plasma Membrane
Extracellular Exosome
Molecular Function
(1->3)-beta-D-glucan Binding
Protein Binding
Carbohydrate Binding
Pattern Recognition Receptor Activity
MHC Protein Binding
Metal Ion Binding
Protein Binding
Biological Process
Leukocyte Activation Involved In Immune Response
Positive Regulation Of Dendritic Cell Cytokine Production
Phagocytosis, Recognition
Inflammatory Response
Cell Recognition
Positive Regulation Of Cell Population Proliferation
Carbohydrate Mediated Signaling
Positive Regulation Of Gene Expression
Detection Of Fungus
Positive Regulation Of Cell Migration
Positive Regulation Of Protein-containing Complex Assembly
Detection Of Molecule Of Fungal Origin
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Superoxide Anion Generation
T Cell Activation
Defense Response To Protozoan
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Innate Immune Response
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Phagocytosis
Positive Regulation Of Lymphocyte Activation
Positive Regulation Of Killing Of Cells Of Other Organism
Positive Regulation Of Respiratory Burst
Cellular Response To Molecule Of Fungal Origin
Positive Regulation Of Monocyte Chemotactic Protein-1 Production
Positive Regulation Of Wound Healing
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Cell Maturation
Multicellular Organism Development
Epithelial Cell Differentiation
Pathways
CLEC7A (Dectin-1) signaling
CLEC7A (Dectin-1) signaling
Drugs
Diseases
Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS
Asthma (
31959851
)
Interacting Genes
47 interacting genes:
ADAM33
AIP
ARL13B
ASGR2
BNIP3
BNIP3L
C14orf180
CALM3
CD53
CD74
CTXN3
CXCL9
FAM3A
FCGR1A
FNDC9
GJB1
HSPD1
IFNGR2
IL1RL1
JAGN1
KLRC1
KTN1
MTIF3
NEMP1
NINJ2
NSG2
OCLN
OLFM4
OPRM1
PTTG1IP
RANBP9
RHOU
SAR1A
SEC22A
SGCB
SMIM3
SPINT1
SUSD3
SYNE4
TEX29
TLCD4
TMEM79
TMPRSS2
TMPRSS4
UPK2
VSIR
ZFPL1
33 interacting genes:
ADGRG3
AMIGO1
ASGR2
ATP6AP2
BSCL2
BTNL9
C3orf52
CD74
CLDN7
CLEC17A
CLEC7A
FCGR1A
FCGR2A
FCGRT
FNDC9
GPA33
HPN
ITM2C
KASH5
KIR2DL3
KIR3DL3
LIME1
PLP1
RNF170
SLC22A23
SMAGP
STOML3
TMEM106C
TMPRSS2
TNFSF11
TNFSF14
UPK1A
ZNRF4
Entrez ID
64581
7379
HPRD ID
08396
10295
Ensembl ID
ENSG00000172243
ENSG00000110375
Uniprot IDs
A0A024RAN9
A0A0S2Z5Q1
Q68D78
Q9BXN2
O00526
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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