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POLR1E and NFKBIB
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology)
HPRD
(in vitro)
POLR1E
NFKBIB
Description
RNA polymerase I subunit E
NFKB inhibitor beta
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Fibrillar Center
Nucleoplasm
Nucleolus
RNA Polymerase I Complex
Nucleus
Cytosol
Molecular Function
RNA Polymerase I General Transcription Initiation Factor Binding
DNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Transcription Coactivator Activity
Protein Binding
Biological Process
RNA Polymerase I Preinitiation Complex Assembly
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Nucleolar Large RRNA Transcription By RNA Polymerase I
Positive Regulation Of Gene Expression, Epigenetic
Transcription, DNA-templated
Signal Transduction
Cytoplasmic Sequestering Of NF-kappaB
Positive Regulation Of Transcription, DNA-templated
Cellular Response To Lipopolysaccharide
Pathways
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
Activation of NF-kappaB in B cells
RIP-mediated NFkB activation via ZBP1
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
TRAF6 mediated NF-kB activation
Drugs
Diseases
GWAS
Interacting Genes
8 interacting genes:
NFKBIB
POLR1A
POLR1B
POLR1C
POLR1G
SIRT7
TAF1C
UBTF
43 interacting genes:
APP
BAK1
BTBD6
BTRC
CDC25A
CHUK
CSNK2A1
CUL1
DNAJA3
ESR2
FHL3
GIT2
IKBKB
IKBKG
KPNA2
LRPPRC
MCC
MTIF2
NCOR2
NDUFB7
NFKB1
NFKB2
NFKBIA
NGFR
NKIRAS1
NKIRAS2
PDCD2
POLR1A
POLR1B
POLR1C
POLR1D
POLR1E
POLR1G
POLR2H
POLR2L
PPARG
RASAL2
REL
RELA
RXRA
SKP1
TSPAN1
VPS52
Entrez ID
64425
4793
HPRD ID
15096
07260
Ensembl ID
ENSG00000137054
ENSG00000104825
Uniprot IDs
B4E005
Q9GZS1
G5E9C2
Q15653
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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