LIN7B and PALS2

Data Source:
BioGRID (two hybrid)

		LIN7B	PALS2
Description		lin-7 homolog B, crumbs cell polarity complex component	protein associated with LIN7 2, MAGUK family member
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane	Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding PDZ Domain Binding L27 Domain Binding	Protein Binding
	Biological Process	Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Basolateral Plasma Membrane	Protein-containing Complex Assembly
Pathways		Dopamine Neurotransmitter Release Cycle RHO GTPases Activate Rhotekin and Rhophilins Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS
Interacting Genes		22 interacting genes: ABCA1 APBA1 ASIC3 BAIAP2 CASK DLG4 ENKD1 GNG13 GRIK2 GRIN2B KCNJ12 KCNJ4 MAK16 MPP2 MPP3 MPP7 NTAQ1 PALS1 PALS2 PSMB1 TCEANC TRAPPC12	30 interacting genes: AATF ABCA1 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A LIN7B LIN7C MT2P1 MTREX NDN NFKB1 PARN RPS20 SMARCA4 SNX9 THOP1
Entrez ID		64130	51678
HPRD ID		10040	09509
Ensembl ID		ENSG00000104863	ENSG00000105926
Uniprot IDs		Q9HAP6	A0A024RA25 B8ZZG1 Q9NZW5
PDB IDs		2DKR
Enriched GO Terms of Interacting Partners?
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