LIN7B and MPP2

Data Source:
BioGRID (two hybrid)

		LIN7B	MPP2
Description		lin-7 homolog B, crumbs cell polarity complex component	membrane palmitoylated protein 2
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GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane	Cytoplasm Cytoskeleton Postsynaptic Density Dendrite Membrane Dendritic Spine Dendritic Shaft
	Molecular Function	Protein Binding Protein Domain Specific Binding PDZ Domain Binding L27 Domain Binding	Protein Binding
	Biological Process	Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Basolateral Plasma Membrane	Protein Homooligomerization Excitatory Postsynaptic Potential Long-term Synaptic Potentiation
Pathways		Dopamine Neurotransmitter Release Cycle RHO GTPases Activate Rhotekin and Rhophilins Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS			Cognitive function ( 24684796)
Interacting Genes		22 interacting genes: ABCA1 APBA1 ASIC3 BAIAP2 CASK DLG4 ENKD1 GNG13 GRIK2 GRIN2B KCNJ12 KCNJ4 MAK16 MPP2 MPP3 MPP7 NTAQ1 PALS1 PALS2 PSMB1 TCEANC TRAPPC12	7 interacting genes: CSNK2B DLG1 ERBIN LIN7A LIN7B LIN7C PLK1
Entrez ID		64130	4355
HPRD ID		10040	02837
Ensembl ID		ENSG00000104863	ENSG00000108852
Uniprot IDs		Q9HAP6	A0A0A0MRU0 A0A0C4DH75 B4DRL7 B4DZ84 D3DX48 D3DX49 Q14168
PDB IDs		2DKR	2E7K
Enriched GO Terms of Interacting Partners?
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