SEMG1 and EAF1

Data Source:
BioGRID (two hybrid)

		SEMG1	EAF1
Description		semenogelin 1	ELL associated factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Protein-containing Complex Extracellular Exosome	Nucleoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Body Nuclear Speck Super Elongation Complex Intracellular Membrane-bounded Organelle Intercellular Bridge
	Molecular Function	Protein Binding Zinc Ion Binding	Transcription Elongation Regulator Activity Protein Binding
	Biological Process	Insemination Antimicrobial Humoral Response Antibacterial Humoral Response Killing Of Cells Of Other Organism Cellular Protein Metabolic Process Sperm Capacitation Coagulation Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Calcium Ion Import Positive Regulation Of Serine-type Endopeptidase Activity Negative Regulation Of Flagellated Sperm Motility	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Pathways		Antimicrobial peptides Amyloid fiber formation	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Bipolar disorder ( 31043756) Blood protein levels ( 28240269) Malaria ( 31844061)
Interacting Genes		9 interacting genes: EAF1 KLK2 KLK3 PRKCA PTPRF SEMG2 TGM1 UBQLN2 UBQLN4	53 interacting genes: AP2M1 APP ARID4B BEND7 BHLHB9 CCDC150 CCDC33 CEP70 CEP76 DNTTIP1 DPPA4 ELL ELL2 ELL3 FAM228A GADD45GIP1 GAS8 GCSAML GOLGA6L9 GRHL3 GTF2H1 GTF2H4 HOMER3 HSF2BP KEAP1 KIAA1328 MAB21L3 MIPOL1 NUMB PAX6 PICK1 PIH1D1 PSME3 RYBP SDCBP SEMG1 SH3RF1 SRP14 STAC3 TCEA2 TFCP2 TFPT TLE5 TNFAIP8 TNNI1 TRAF2 TRIM62 VAX1 YAF2 ZBTB14 ZNF143 ZNF202 ZNF620
Entrez ID		6406	85403
HPRD ID		01641	12209
Ensembl ID		ENSG00000124233	ENSG00000144597
Uniprot IDs		P04279	Q96JC9
PDB IDs
Enriched GO Terms of Interacting Partners?
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