TRAPPC2 and NME4

Data Source:
BioGRID (two hybrid)

		TRAPPC2	NME4
Description		trafficking protein particle complex subunit 2	NME/NM23 nucleoside diphosphate kinase 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Matrix
	Molecular Function	Protein Binding Transcription Factor Binding Ion Channel Binding	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Metal Ion Binding Cardiolipin Binding
	Biological Process	Skeletal System Development Regulation Of Transcription, DNA-templated Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPII Vesicle Coating	Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Lipid Transport Nucleoside Metabolic Process Nucleobase-containing Small Molecule Interconversion
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	Interconversion of nucleotide di- and triphosphates
Drugs
Diseases		Spondyloepiphyseal dysplasia tarda
GWAS			Body mass index ( 26426971) Red blood cell traits ( 23446634)
Interacting Genes		37 interacting genes: ABRA CLIC1 CLIC2 DAPK1 EIF3C ENO1 ENO3 EPS15L1 HLA-E INCA1 JOSD2 KCTD1 LSM3 MBD3L1 MFHAS1 NICN1 NME4 NR5A1 PITX1 PYGM REPS1 SLC25A35 SNAPC5 TEPSIN TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9 UQCC2 ZBED1 ZBTB38 ZNF438 ZNF655 ZRANB1	40 interacting genes: ABI2 ARMC7 ATPAF2 C14orf119 C1orf109 CABP2 CABP5 CCDC102B CCDC57 CDKN2D CFAP206 CIB1 CIB3 CIDEB CLNK DTX2 HDAC7 HSF2BP LMO4 LSM8 MKRN3 MLH1 NME1 NME1-NME2 NME7 NUTF2 NXF1 POLR1C PSMB1 SOCS3 SPG21 SUV39H2 TNS4 TRAPPC2 TRAPPC2B TRIP13 TSSK3 TTC19 UBL5 ZBTB16
Entrez ID		6399	4833
HPRD ID		02189	03489
Ensembl ID		ENSG00000196459	ENSG00000103202
Uniprot IDs		P0DI81 P0DI82 Q6IBE5	A0A087WVT9 O00746
PDB IDs			1EHW
Enriched GO Terms of Interacting Partners?
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