TRAPPC2 and CLIC2

Data Source:
HPRD (in vivo)

		TRAPPC2	CLIC2
Description		trafficking protein particle complex subunit 2	chloride intracellular channel 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Chloride Channel Complex
	Molecular Function	Protein Binding Transcription Factor Binding Ion Channel Binding	Glutathione Transferase Activity Glutathione Peroxidase Activity Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding
	Biological Process	Skeletal System Development Regulation Of Transcription, DNA-templated Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPII Vesicle Coating	Glutathione Metabolic Process Signal Transduction Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Binding Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Oxidant Detoxification Chloride Transmembrane Transport
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	Stimuli-sensing channels Ion homeostasis
Drugs
Diseases		Spondyloepiphyseal dysplasia tarda
GWAS
Interacting Genes		37 interacting genes: ABRA CLIC1 CLIC2 DAPK1 EIF3C ENO1 ENO3 EPS15L1 HLA-E INCA1 JOSD2 KCTD1 LSM3 MBD3L1 MFHAS1 NICN1 NME4 NR5A1 PITX1 PYGM REPS1 SLC25A35 SNAPC5 TEPSIN TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9 UQCC2 ZBED1 ZBTB38 ZNF438 ZNF655 ZRANB1	4 interacting genes: NEDD4 NEDD4L TPRN TRAPPC2
Entrez ID		6399	1193
HPRD ID		02189	02139
Ensembl ID		ENSG00000196459	ENSG00000155962
Uniprot IDs		P0DI81 P0DI82 Q6IBE5	O15247
PDB IDs			2PER 2R4V 2R5G
Enriched GO Terms of Interacting Partners?
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