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CHTF18 and RFC4
Data Source:
HPRD
(in vivo)
CHTF18
RFC4
Description
chromosome transmission fidelity factor 18
replication factor C subunit 4
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Membrane
Ctf18 RFC-like Complex
Nucleus
Nucleoplasm
DNA Replication Factor C Complex
Ctf18 RFC-like Complex
Elg1 RFC-like Complex
Molecular Function
DNA Binding
DNA Clamp Loader Activity
Protein Binding
ATP Binding
Single-stranded DNA Helicase Activity
DNA Clamp Loader Activity
Protein Binding
ATP Binding
Single-stranded DNA Helicase Activity
Biological Process
DNA Replication
Cell Cycle
DNA Duplex Unwinding
Positive Regulation Of DNA-directed DNA Polymerase Activity
DNA Replication
DNA-dependent DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair, DNA Incision, 5'-to Lesion
Nucleotide-excision Repair, DNA Gap Filling
Translesion Synthesis
Telomere Maintenance Via Semi-conservative Replication
DNA Duplex Unwinding
Nucleotide-excision Repair, DNA Incision
Error-prone Translesion Synthesis
DNA Damage Response, Detection Of DNA Damage
Error-free Translesion Synthesis
Positive Regulation Of DNA-directed DNA Polymerase Activity
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Polymerase switching on the C-strand of the telomere
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Polymerase switching on the C-strand of the telomere
Activation of ATR in response to replication stress
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Regulation of TP53 Activity through Phosphorylation
Polymerase switching
G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Activated partial thromboplastin time (
22703881
)
Interacting Genes
5 interacting genes:
CRK
PCNA
RFC4
RFC5
STAT3
13 interacting genes:
BRD4
CDK4
CHTF18
HDAC1
PCNA
PTEN
RAD17
RFC2
RFC3
RFC5
RNF41
SUMO2
TRIM28
Entrez ID
63922
5984
HPRD ID
13059
00022
Ensembl ID
ENSG00000127586
ENSG00000163918
Uniprot IDs
Q8WVB6
P35249
PDB IDs
6VVO
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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