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SDCBP and STX1A
Data Source:
HPRD
(in vivo, in vitro)
SDCBP
STX1A
Description
syndecan binding protein
syntaxin 1A
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Cytoskeleton
Plasma Membrane
Interleukin-5 Receptor Complex
Adherens Junction
Focal Adhesion
Membrane
Nuclear Membrane
Azurophil Granule Lumen
Melanosome
Membrane Raft
Synapse
Extracellular Exosome
Blood Microparticle
Extracellular Vesicle
Extracellular Region
Cytosol
Plasma Membrane
Synaptic Vesicle
Voltage-gated Potassium Channel Complex
Endomembrane System
Postsynaptic Density
Integral Component Of Membrane
Secretory Granule
Integral Component Of Synaptic Vesicle Membrane
Axon
SNARE Complex
Nuclear Membrane
Actomyosin
Neuron Projection
Presynaptic Active Zone Membrane
Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex
Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex
Synaptobrevin 2-SNAP-25-syntaxin-1a Complex
Glutamatergic Synapse
Integral Component Of Presynaptic Membrane
Molecular Function
Frizzled Binding
Interleukin-5 Receptor Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Cytoskeletal Anchor Activity
Identical Protein Binding
Syndecan Binding
Protein Heterodimerization Activity
Protein N-terminus Binding
SNARE Binding
SNAP Receptor Activity
Protein Binding
Calcium Channel Inhibitor Activity
Chloride Channel Inhibitor Activity
Kinase Binding
Protein Domain Specific Binding
Myosin Head/neck Binding
Identical Protein Binding
ATP-dependent Protein Binding
Ion Channel Binding
Protein-containing Complex Binding
Protein N-terminus Binding
Calcium-dependent Protein Binding
Biological Process
Negative Regulation Of Receptor Internalization
Protein Targeting To Membrane
Substrate-dependent Cell Migration, Cell Extension
Chemical Synaptic Transmission
Regulation Of Mitotic Cell Cycle
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Actin Cytoskeleton Organization
Positive Regulation Of Cell Growth
Positive Regulation Of Cell Migration
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Intracellular Signal Transduction
Positive Regulation Of Phosphorylation
Neutrophil Degranulation
Positive Regulation Of JNK Cascade
Ephrin Receptor Signaling Pathway
Positive Regulation Of Exosomal Secretion
Positive Regulation Of Extracellular Exosome Assembly
Positive Regulation Of Neurotransmitter Secretion
Intracellular Protein Transport
Exocytosis
Vesicle Fusion
Neurotransmitter Secretion
Response To Gravity
Positive Regulation Of Norepinephrine Secretion
Regulation Of Synaptic Vesicle Priming
Glutamate Secretion
Synaptic Vesicle Exocytosis
Synaptic Vesicle Docking
Protein Sumoylation
Calcium-ion Regulated Exocytosis
Cytokine-mediated Signaling Pathway
Insulin Secretion
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Secretion By Cell
Positive Regulation Of Catecholamine Secretion
SNARE Complex Assembly
Positive Regulation Of Calcium Ion-dependent Exocytosis
Vesicle Docking
Synaptic Vesicle Endocytosis
Regulation Of Insulin Secretion
Protein Localization To Membrane
Positive Regulation Of Excitatory Postsynaptic Potential
Pathways
Ephrin signaling
Neurofascin interactions
RIPK1-mediated regulated necrosis
Regulation of necroptotic cell death
Neutrophil degranulation
Serotonin Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Insulin processing
Regulation of insulin secretion
Other interleukin signaling
Toxicity of botulinum toxin type C (botC)
LGI-ADAM interactions
Neurexins and neuroligins
GABA synthesis, release, reuptake and degradation
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS
Low density lipoprotein cholesterol levels (
32154731
)
Lymphocyte counts (
32888494
)
Monocyte count (
32888494
)
Triglyceride levels (
32154731
)
Malaria (
31844061
)
Triglyceride levels (
32203549
)
Interacting Genes
307 interacting genes:
ABI2
ANKRD33
ANKRD36B
ANKRD40
ANP32B
APIP
ARFIP2
ARL6IP1
BCL2L15
BEND7
C11orf68
C1orf109
C1orf35
C2CD2L
CABP5
CADM1
CADPS
CALCOCO2
CALM1
CALM2
CALM3
CAV2
CBR3
CBY2
CCDC102B
CCDC106
CD6
CD63
CDA
CDC34
CDCP1
CDIPT
CDKN2D
CEP55
CEP85
CGGBP1
CHIC2
CHMP1A
CLK2
CLK3
CMTM5
COX4I1
CRX
CRYAA
CRYAA2
CT45A1
CT45A10
CT45A3
CT45A5
CTBP2
CTDSP1
CUTC
CYHR1
DCTD
DCTPP1
DDX39B
DERL3
DMC1
DNM2
DRAP1
DTNBP1
DYNLT1
EAF1
EDARADD
EFNB1
EFNB2
EIF1AD
EIF5A
EIF5A2
ELAVL1
EMILIN3
ENOX1
ENTR1
EPHB2
ERICH2
EXOSC4
FADD
FAM118A
FAM118B
FAM9A
FAM9B
FHL3
FHL5
FLAD1
FOXP2
FTH1
FTL
GET4
GGPS1
GKAP1
GNMT
GOLT1B
GPATCH11
GPR37
GRIA1
GRIA2
GRIA3
GRIA4
GRIK1
GRIK2
GRM2
GRM3
GRM7
GRXCR1
GSC2
GSG1
HEXIM2
HHAT
HIVEP1
HMBOX1
HMGB3
HNRNPC
HOMER3
HOMEZ
HOXA1
HOXA7
HPRT1
HSBP1
HSF2BP
HUS1
ID3
IGFBP6
IHO1
IKZF1
IL5RA
INO80E
KATNBL1
KCNH1
KCNJ2
KCTD1
KCTD6
KCTD9
KHDRBS2
KLHL12
KLHL2
KRT14
KRTAP1-3
KRTAP1-5
KRTAP10-3
KRTAP10-7
KRTAP5-9
LDB2
LDHB
LDOC1
LEPROTL1
LGALS2
LSM6
LURAP1L
LZTFL1
MAD2L1
MAPK9
MAPRE3
MATN4
MBD3
MED4
MEOX1
MEOX2
MGLL
MID2
MINDY3
MKRN1
MOBP
MRFAP1
MRFAP1L1
MTUS2
MYBPC2
MYLIP
N4BP3
NADK
NAGK
NAPB
NECAB2
NF2
NFASC
NKAPD1
NOTCH2NLA
NT5C2
OCM
ODAM
OPTN
OSTF1
PCBD1
PCYT1A
PDCD6IP
PDE4DIP
PDE9A
PDLIM4
PDZK1IP1
PFDN5
PHC2
PHF11
PIH1D2
PNMA1
PNMA2
POLR2J
POLR3K
PPARA
PRPF38A
PRPF40A
PRR13
PSMB3
PSMC6
PSME2
PSTPIP1
PTEN
PTPRJ
PTS
PUF60
PYCR3
RAB5A
RALY
RBM39
REEP6
REL
RIC8A
RNF11
RNH1
ROPN1
RP9
RP9P
RPIA
RPL22
RPRD1A
RPRM
RPS26
RRM2
RRS1
RTL8B
RTN1
RUNDC3A
S100B
SCG3
SCML1
SDC1
SDC2
SDC4
SDCBP2
SEPTIN1
SEPTIN3
SET
SFT2D1
SIAH1
SLC50A1
SLC6A5
SMARCA2
SNRPA
SNX1
SOX4
SPANXN3
SREK1IP1
SRSF11
SRSF3
SRSF7
SSC5D
SSNA1
STX1A
SUB1
SULT1B1
SYNGR1
SYPL1
SYS1
TCF21
TCF4
TDO2
TEKT1
TFCP2
TGFA
THG1L
TIFA
TKFC
TLE5
TMCO2
TMEM17
TMEM239
TNFAIP8
TNFAIP8L3
TNKS
TRAF5
TRARG1
TRIM27
TRIM32
TRIM38
TRIM54
TRIP13
TSN
UBB
UBC
UBE2A
UBE2K
UBE2R2
ULK1
WASHC1
WASHC3
WASL
WDR91
YIF1A
ZBTB14
ZBTB8A
ZCCHC10
ZCCHC17
ZMYND12
ZNF343
ZNF485
ZNF660
ZNF768
ZRANB1
ZSCAN23
167 interacting genes:
AARD
ABCC9
ABI3
AGTRAP
AIG1
ANKRD46
AOC3
APBA1
APOL2
APOL3
AQP3
ARL13B
ATP4B
ATP6V1B1
BET1
BLOC1S6
BNIP1
BTN2A2
C1GALT1
C4orf3
CACNA1D
CCSER2
CD81
CDC37
CDK5
CFTR
CLEC1A
CLN6
CMTM7
CPLX1
CSNK2A1
CSNK2A2
CXCL16
CYB5B
DAPK1
DDX49
EBAG9
EMD
ERG28
ETNK2
FAM3C
GIMAP1
GIMAP5
GOLM2
GOSR2
GPM6B
HMOX1
JAGN1
KCNB1
KIFC3
MAL
MALL
MIP
MMGT1
NAPA
NAPB
NINJ2
NKG7
NRM
NSF
PGAP2
PLN
PLP1
PLPP4
PLPP6
PNLIPRP1
PSMA3
RAB27A
RAB3IL1
RIMS1
RMDN2
RNF4
RTP2
SCNN1A
SCNN1B
SCNN1G
SDCBP
SEC22A
SEC22B
SEPTIN2
SEPTIN5
SERP1
SERP2
SLC6A1
SLC6A2
SLC6A3
SLC6A4
SLC6A5
SLC6A9
SMIM1
SMIM3
SNAP23
SNAP25
SNAP29
SNAP47
SNORC
SNPH
STRIT1
STX10
STX11
STX12
STX16
STX2
STX3
STX4
STX5
STX6
STX7
STX8
STXBP1
STXBP2
STXBP5
STXBP6
SUMO1P1
SYT1
SYT4
SYT7
SYTL4
TCEANC
TMEM100
TMEM120A
TMEM128
TMEM14C
TMEM199
TMEM222
TMEM254
TMEM41A
TMEM60
TNF
TRAF3IP3
TRDMT1
TSGA10IP
TSNARE1
TXLNA
TXLNB
UBE2I
UBTFL1
UNC13B
UPK1B
USE1
VAMP1
VAMP2
VAMP3
VAMP4
VAMP5
VAMP7
VAMP8
VAPB
VIM
VPS11
VPS16
VPS18
VSTM4
VTI1B
ZFPL1
ZNF12
ZNF136
ZNF250
ZNF440
ZNF441
ZNF479
ZNF490
ZNF557
ZNF696
ZNF707
ZNF785
ZNF835
Entrez ID
6386
6804
HPRD ID
03741
01721
Ensembl ID
ENSG00000137575
ENSG00000106089
Uniprot IDs
A0A024R7Z5
B4DHN5
G5EA09
O00560
Q16623
Q75ME0
PDB IDs
1N99
1NTE
1OBX
1OBY
1OBZ
1R6J
1V1T
1W9E
1W9O
1W9Q
1YBO
4Z33
Enriched GO Terms of Interacting Partners
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