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CEACAM1 and MAP3K10
Data Source:
HPRD
(in vitro, in vivo)
CEACAM1
MAP3K10
Description
CEA cell adhesion molecule 1
mitogen-activated protein kinase kinase kinase 10
Image
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Cell-cell Junction
Adherens Junction
Basal Plasma Membrane
Cell Surface
Membrane
Integral Component Of Membrane
Apical Plasma Membrane
Lateral Plasma Membrane
Cell Junction
Transport Vesicle Membrane
Microvillus Membrane
Specific Granule Membrane
T Cell Receptor Complex
Extracellular Exosome
Tertiary Granule Membrane
Cytoplasm
Molecular Function
Molecular_function
Actin Binding
Protein Binding
Calmodulin Binding
Bile Acid Transmembrane Transporter Activity
Kinase Binding
Protein Phosphatase Binding
Filamin Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein Dimerization Activity
Protein Tyrosine Kinase Binding
Transcription Corepressor Activity
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
JUN Kinase Kinase Kinase Activity
ATP Binding
Protein Homodimerization Activity
BHLH Transcription Factor Binding
Biological Process
Angiogenesis
Regulation Of Cell Growth
Blood Vessel Development
Negative Regulation Of T Cell Mediated Cytotoxicity
Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target
Negative Regulation Of Protein Kinase Activity
Cell Adhesion
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Integrin-mediated Signaling Pathway
Regulation Of Endothelial Cell Migration
Regulation Of Phosphatidylinositol 3-kinase Signaling
Bile Acid And Bile Salt Transport
Cell Migration
Regulation Of Cell Migration
Negative Regulation Of Granulocyte Differentiation
Negative Regulation Of Interleukin-1 Production
Cellular Response To Insulin Stimulus
Common Myeloid Progenitor Cell Proliferation
Insulin Receptor Internalization
Granulocyte Colony-stimulating Factor Signaling Pathway
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Vascular Permeability
Neutrophil Degranulation
Negative Regulation Of Cytotoxic T Cell Degranulation
Wound Healing, Spreading Of Cells
Regulation Of Endothelial Cell Differentiation
Negative Regulation Of Fatty Acid Biosynthetic Process
Negative Regulation Of T Cell Receptor Signaling Pathway
Leukocyte Migration
Negative Regulation Of Lipid Biosynthetic Process
Regulation Of Blood Vessel Remodeling
Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Platelet Aggregation
Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Insulin Catabolic Process
Regulation Of Homophilic Cell Adhesion
Regulation Of Sprouting Angiogenesis
Negative Regulation Of Hepatocyte Proliferation
Positive Regulation Of Vasculogenesis
Apoptotic Process
Signal Transduction
Smoothened Signaling Pathway
JNK Cascade
Activation Of JNKK Activity
Activation Of JUN Kinase Activity
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Positive Regulation Of Apoptotic Process
Negative Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of JUN Kinase Activity
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of JNK Cascade
Protein Autophosphorylation
Pathways
Fibronectin matrix formation
Cell surface interactions at the vascular wall
Neutrophil degranulation
Drugs
Technetium Tc-99m arcitumomab
Fostamatinib
Diseases
GWAS
Birth weight (
31043758
)
Resting heart rate (
27798624
)
Interacting Genes
18 interacting genes:
ADRB2
ANXA2
CARTPT
CD209
CEACAM3
CEACAM5
CEACAM6
CEACAM7
CEACAM8
EGFR
FLNA
INSR
MAP3K10
PTPN11
PTPN6
PXN
SHC1
SRC
31 interacting genes:
ABL2
CDC42
CEACAM1
CLTC
CNKSR1
COPS2
DLG4
DNM1
DNM1L
GARS1
HGS
HTT
KIF17
KIF3A
KIF3B
KIFAP3
MAP2K4
MAP3K21
MAPK1
MAPK14
MAPK8IP1
MAPK8IP2
MAPK9
NEUROD1
PHB
RAC1
RACGAP1
SH3RF1
SMURF1
TUBB
YWHAE
Entrez ID
634
4294
HPRD ID
00191
02533
Ensembl ID
ENSG00000079385
ENSG00000130758
Uniprot IDs
P13688
Q3KRG8
Q02779
PDB IDs
2GK2
4QXW
4WHD
5DZL
6AW2
6GBG
6GBH
2RF0
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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