MAPK12 and RCSD1

Data Source:
BioGRID (enzymatic study)

		MAPK12	RCSD1
Description		mitogen-activated protein kinase 12	RCSD domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol	Actin Filament
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding	Actin Filament Binding
	Biological Process	MAPK Cascade DNA Damage Induced Protein Phosphorylation Cell Cycle Arrest Signal Transduction Muscle Organ Development Positive Regulation Of Peptidase Activity Peptidyl-serine Phosphorylation Intracellular Signal Transduction Myoblast Differentiation Positive Regulation Of Muscle Cell Differentiation	Skeletal Muscle Contraction Cellular Hyperosmotic Response
Pathways		NOD1/2 Signaling Pathway p38MAPK events Activation of PPARGC1A (PGC-1alpha) by phosphorylation DSCAM interactions VEGFA-VEGFR2 Pathway Myogenesis Myogenesis Negative regulation of MAPK pathway
Drugs		Minocycline Phosphonothreonine Phosphoaminophosphonic Acid-Adenylate Ester KC706 CEP-1347
Diseases
GWAS		Acne (severe) ( 24927181) Diverticular disease ( 30177863) Triiodothyronine levels and thyroxine levels ( 30843173)	Asthma ( 31959851) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		29 interacting genes: DLG1 DLG2 DLG3 DLG4 DUSP1 EEF2K ERBIN GRB2 GTF2I HTRA2 MAP2K3 MAP2K4 MAP2K6 MAPKAPK5 MAPT MBP PATJ PDGFRL PKN1 PTPN3 PTPN4 RCSD1 RGS3 SH3BP5 SIAH1 SNTA1 SNTB1 SRPK1 TERF1	3 interacting genes: MAPK12 MAPKAPK2 MAPKAPK3
Entrez ID		6300	92241
HPRD ID		03868	10077
Ensembl ID		ENSG00000188130	ENSG00000198771
Uniprot IDs		P53778 Q6N076	B7ZKW8 Q6JBY9
PDB IDs		1CM8 4QUM 6UNA
Enriched GO Terms of Interacting Partners?
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