RAP2A and TM7SF2

Data Source:
BioGRID (two hybrid)

		RAP2A	TM7SF2
Description		RAP2A, member of RAS oncogene family	transmembrane 7 superfamily member 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Midbody Recycling Endosome Recycling Endosome Membrane	Nuclear Inner Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Integral Component Of Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle Receptor Complex
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding GDP Binding	Protein Binding Oxidoreductase Activity, Acting On The CH-CH Group Of Donors Delta14-sterol Reductase Activity NADP Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Cellular Protein Localization Cellular Response To Drug Establishment Of Protein Localization Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane	Cholesterol Biosynthetic Process Sterol Biosynthetic Process Regulation Of Cholesterol Biosynthetic Process
Pathways			Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs		Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Peripheral artery disease ( 26488411)	Blood protein levels ( 28240269)
Interacting Genes		32 interacting genes: ACVR1 AFDN ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 NEDD4 PLG RAF1 RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGL1 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK	4 interacting genes: CHRM4 CYSRT1 LCE2C RAP2A
Entrez ID		5911	7108
HPRD ID		01547	04564
Ensembl ID		ENSG00000125249	ENSG00000149809
Uniprot IDs		P10114	A0A024R577 O76062
PDB IDs		1KAO 2RAP 3RAP
Enriched GO Terms of Interacting Partners?
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