RAD23A and SH3RF1

Data Source:
BioGRID (two hybrid)

		RAD23A	SH3RF1
Description		RAD23 homolog A, nucleotide excision repair protein	SH3 domain containing ring finger 1
Image			No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex Centriolar Satellite Intracellular Membrane-bounded Organelle	Golgi Apparatus Cytosol Lamellipodium Perinuclear Region Of Cytoplasm
	Molecular Function	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Kinase Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Proteasome Binding Ubiquitin-specific Protease Binding	MAP-kinase Scaffold Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Nucleotide-excision Repair Viral Process Protein Deubiquitination Protein Destabilization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Cell Cycle	Neuron Migration Viral Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of JNK Cascade Protein Autoubiquitination Regulation Of CD8-positive, Alpha-beta T Cell Proliferation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353)	Alzheimer disease and age of onset ( 26830138) Body fat mass ( 28552196) Body mass index ( 28552196) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Night sleep phenotypes ( 27126917) Photic sneeze reflex ( 27182965) Schizophrenia ( 30285260) Weight ( 28552196)
Interacting Genes		76 interacting genes: A2M ADRM1 ANKRD40 ATXN3 ATXN7 CCNA2 CDC37 CHEK1 CNTROB CREBBP DAZAP2 DBI ECSIT EP300 EWSR1 FILIP1 GTF2H1 HSPB1 IFIT3 IFIT5 KRTAP12-2 LOXL4 MAP3K1 MAST1 MDM2 MINDY3 MKRN1 MPG NEDD8 NGLY1 NUTM2F PDE6D PHAX PI4K2A PRKN PSEN1 PSMC5 PSMD4 RABGEF1 REL RNF115 RNF32 RNF41 RPN1 RPS27A SH3RF1 SMURF1 SQSTM1 TNFAIP3 TRAF2 TRAF3 TRAF5 TRAF6 TRIM39 TRIM50 TRIM54 TRIM55 TRIM8 TRIP6 UBA52 UBB UBC UBE3A UBE4B UBL7 UBQLN2 UBQLN4 UBXN1 UIMC1 USP25 VAV2 XPC ZBTB26 ZBTB44 ZBTB8A ZFAND6	69 interacting genes: ACAP1 ADAM15 AKT1 AKT2 ARHGEF15 ATN1 ATXN7L2 CBLB CCDC6 DLGAP4 DMRTB1 DNM2 EAF1 EVL FGD1 FHL2 GGN HERPUD1 KCNJ1 LCP2 MAP3K10 MAP3K11 MAP3K12 MAP3K9 MAP4K3 MTURN NAF1 NCF1 NFKBID NHSL2 NUTM2F ONECUT3 PAK2 PDCD6IP PRAM1 PRB3 PRR20A PRR20B PRR20C PRR20D PRR20E PXN RAC1 RACGAP1 RAD23A RIN1 RNF208 RUNX1T1 SEMA6A SF3A2 SH2D4A SH3BP2 SH3D19 SIAH1 SLC22A5 SOCS7 SORBS2 SUFU SYNPO2L TP53BP2 UBASH3A UBE2D1 UBE2D3 UBE2K UBE2N VPS37C WASL WIPF1 XIRP1
Entrez ID		5886	57630
HPRD ID		07191	15335
Ensembl ID		ENSG00000179262	ENSG00000154447
Uniprot IDs		A0A024R7G8 A8K1J3 P54725	Q7Z6J0
PDB IDs		1DV0 1F4I 1IFY 1OQY 1P98 1P9D 1QZE 1TP4 1ZO6 2WYQ 5XBO
Enriched GO Terms of Interacting Partners?
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