RAB27B and EFHD1

Data Source:
BioGRID (affinity chromatography technology)

		RAB27B	EFHD1
Description		RAB27B, member RAS oncogene family	EF-hand domain family member D1
Image			No pdb structure
GO Annotations	Cellular Component	Late Endosome Golgi Stack Plasma Membrane Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Platelet Dense Granule Membrane Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane Axon Cytoplasm	Mitochondrion Mitochondrial Inner Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding	Calcium Ion Binding Calcium Ion Sensor Activity
	Biological Process	Platelet Degranulation Melanosome Transport Positive Regulation Of Exocytosis Synaptic Vesicle Endocytosis Multivesicular Body Sorting Pathway Anterograde Axonal Protein Transport	Neuron Projection Development Regulation Of Cellular Hyperosmotic Salinity Response
Pathways		Platelet degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Adult body size ( 32376654) Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 28892062) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Depression ( 29700475) Serum uric acid levels in response to allopurinol in gout ( 25676789)	Alanine transaminase levels ( 29403010) Aspartate aminotransferase levels ( 29403010) Coronary artery disease ( 32469254) Gamma glutamyl transferase levels ( 29403010) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656 30285260)
Interacting Genes		11 interacting genes: DHPS GORASP2 MLPH MYRIP RPH3A RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D	1 interacting genes: PSEN1
Entrez ID		5874	80303
HPRD ID		04846	13265
Ensembl ID		ENSG00000041353	ENSG00000115468
Uniprot IDs		O00194	Q8WYH2 Q9BUP0
PDB IDs		2F7S
Enriched GO Terms of Interacting Partners?
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